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On the mechanism of action of SJ-172550 in inhibiting the interaction of MDM4 and p53.
Bista M, Smithson D, Pecak A, Salinas G, Pustelny K, Min J, Pirog A, Finch K, Zdzalik M, Waddell B, Wladyka B, Kedracka-Krok S, Dyer MA, Dubin G, Guy RK. Bista M, et al. Among authors: guy rk. PLoS One. 2012;7(6):e37518. doi: 10.1371/journal.pone.0037518. Epub 2012 Jun 4. PLoS One. 2012. PMID: 22675482 Free PMC article.
8-Triazolylpurines: Towards Fluorescent Inhibitors of the MDM2/p53 Interaction.
Pettersson M, Bliman D, Jacobsson J, Nilsson JR, Min J, Iconaru L, Guy RK, Kriwacki RW, Andréasson J, Grøtli M. Pettersson M, et al. Among authors: guy rk. PLoS One. 2015 May 5;10(5):e0124423. doi: 10.1371/journal.pone.0124423. eCollection 2015. PLoS One. 2015. PMID: 25942498 Free PMC article.
Identification and characterization of the first small molecule inhibitor of MDMX.
Reed D, Shen Y, Shelat AA, Arnold LA, Ferreira AM, Zhu F, Mills N, Smithson DC, Regni CA, Bashford D, Cicero SA, Schulman BA, Jochemsen AG, Guy RK, Dyer MA. Reed D, et al. Among authors: guy rk. J Biol Chem. 2010 Apr 2;285(14):10786-96. doi: 10.1074/jbc.M109.056747. Epub 2010 Jan 15. J Biol Chem. 2010. PMID: 20080970 Free PMC article.
Inactivation of the p53 pathway in retinoblastoma.
Laurie NA, Donovan SL, Shih CS, Zhang J, Mills N, Fuller C, Teunisse A, Lam S, Ramos Y, Mohan A, Johnson D, Wilson M, Rodriguez-Galindo C, Quarto M, Francoz S, Mendrysa SM, Guy RK, Marine JC, Jochemsen AG, Dyer MA. Laurie NA, et al. Among authors: guy rk. Nature. 2006 Nov 2;444(7115):61-6. doi: 10.1038/nature05194. Nature. 2006. PMID: 17080083
173 results