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HIPK2 controls cytokinesis and prevents tetraploidization by phosphorylating histone H2B at the midbody.
Rinaldo C, Moncada A, Gradi A, Ciuffini L, D'Eliseo D, Siepi F, Prodosmo A, Giorgi A, Pierantoni GM, Trapasso F, Guarguaglini G, Bartolazzi A, Cundari E, Schininà ME, Fusco A, Soddu S. Rinaldo C, et al. Among authors: bartolazzi a. Mol Cell. 2012 Jul 13;47(1):87-98. doi: 10.1016/j.molcel.2012.04.029. Epub 2012 May 31. Mol Cell. 2012. PMID: 22658722 Free article.
Repression of the antiapoptotic molecule galectin-3 by homeodomain-interacting protein kinase 2-activated p53 is required for p53-induced apoptosis.
Cecchinelli B, Lavra L, Rinaldo C, Iacovelli S, Gurtner A, Gasbarri A, Ulivieri A, Del Prete F, Trovato M, Piaggio G, Bartolazzi A, Soddu S, Sciacchitano S. Cecchinelli B, et al. Among authors: bartolazzi a. Mol Cell Biol. 2006 Jun;26(12):4746-57. doi: 10.1128/MCB.00959-05. Mol Cell Biol. 2006. PMID: 16738336 Free PMC article.
Mice with reduced expression of the telomere-associated protein Ft1 develop p53-sensitive progeroid traits.
La Torre M, Merigliano C, Burla R, Mottini C, Zanetti G, Del Giudice S, Carcuro M, Virdia I, Bucciarelli E, Manni I, Vinciguerra GR, Piaggio G, Riminucci M, Cumano A, Bartolazzi A, Vernì F, Soddu S, Gatti M, Saggio I. La Torre M, et al. Among authors: bartolazzi a. Aging Cell. 2018 Aug;17(4):e12730. doi: 10.1111/acel.12730. Epub 2018 Apr 10. Aging Cell. 2018. PMID: 29635765 Free PMC article.
MRE11 inhibition highlights a replication stress-dependent vulnerability of MYCN-driven tumors.
Petroni M, Sardina F, Infante P, Bartolazzi A, Locatelli E, Fabretti F, Di Giulio S, Capalbo C, Cardinali B, Coppa A, Tessitore A, Colicchia V, Sahùn Roncero M, Belardinilli F, Di Marcotullio L, Soddu S, Comes Franchini M, Petricci E, Gulino A, Giannini G. Petroni M, et al. Among authors: bartolazzi a. Cell Death Dis. 2018 Aug 30;9(9):895. doi: 10.1038/s41419-018-0924-z. Cell Death Dis. 2018. PMID: 30166519 Free PMC article.
124 results