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The importance of chronobiology to drug discovery.
Farrow SN, Solari R, Willson TM. Farrow SN, et al. Expert Opin Drug Discov. 2012 Jul;7(7):535-41. doi: 10.1517/17460441.2012.689283. Epub 2012 Jun 2. Expert Opin Drug Discov. 2012. PMID: 22657273
Optimized chemical probes for REV-ERBα.
Trump RP, Bresciani S, Cooper AW, Tellam JP, Wojno J, Blaikley J, Orband-Miller LA, Kashatus JA, Boudjelal M, Dawson HC, Loudon A, Ray D, Grant D, Farrow SN, Willson TM, Tomkinson NC. Trump RP, et al. Among authors: farrow sn. J Med Chem. 2013 Jun 13;56(11):4729-37. doi: 10.1021/jm400458q. Epub 2013 May 23. J Med Chem. 2013. PMID: 23656296 Free PMC article.
A zebrafish compound screen reveals modulation of neutrophil reverse migration as an anti-inflammatory mechanism.
Robertson AL, Holmes GR, Bojarczuk AN, Burgon J, Loynes CA, Chimen M, Sawtell AK, Hamza B, Willson J, Walmsley SR, Anderson SR, Coles MC, Farrow SN, Solari R, Jones S, Prince LR, Irimia D, Rainger GE, Kadirkamanathan V, Whyte MK, Renshaw SA. Robertson AL, et al. Among authors: farrow sn. Sci Transl Med. 2014 Feb 26;6(225):225ra29. doi: 10.1126/scitranslmed.3007672. Sci Transl Med. 2014. PMID: 24574340 Free PMC article.
Identification of benzopyrone as a common structural feature in compounds with anti-inflammatory activity in a zebrafish phenotypic screen.
Robertson AL, Ogryzko NV, Henry KM, Loynes CA, Foulkes MJ, Meloni MM, Wang X, Ford C, Jackson M, Ingham PW, Wilson HL, Farrow SN, Solari R, Flower RJ, Jones S, Whyte MK, Renshaw SA. Robertson AL, et al. Among authors: farrow sn. Dis Model Mech. 2016 Jun 1;9(6):621-32. doi: 10.1242/dmm.024935. Epub 2016 Apr 14. Dis Model Mech. 2016. PMID: 27079522 Free PMC article.
The circadian clock and asthma.
Durrington HJ, Farrow SN, Loudon AS, Ray DW. Durrington HJ, et al. Among authors: farrow sn. Thorax. 2014 Jan;69(1):90-2. doi: 10.1136/thoraxjnl-2013-203482. Epub 2013 May 23. Thorax. 2014. PMID: 23704227
73 results