Ijzerman AP - Search Results

1

Multi-objective evolutionary design of adenosine receptor ligands.

van der Horst E, Marqués-Gallego P, Mulder-Krieger T, van Veldhoven J, Kruisselbrink J, Aleman A, Emmerich MT, Brussee J, Bender A, Ijzerman AP. van der Horst E, et al. Among authors: ijzerman ap. J Chem Inf Model. 2012 Jul 23;52(7):1713-21. doi: 10.1021/ci2005115. Epub 2012 Jun 21. J Chem Inf Model. 2012. PMID: 22647079

2

Molecular modeling of adenosine receptors. I. The ligand binding site on the A1 receptor.

IJzerman AP, Van Galen PJ, Jacobson KA. IJzerman AP, et al. Drug Des Discov. 1992;9(1):49-67. Drug Des Discov. 1992. PMID: 1457698 Free PMC article.

3

A model for the antagonist binding site on the adenosine A1 receptor, based on steric, electrostatic, and hydrophobic properties.

van Galen PJ, van Vlijmen HW, IJzerman AP, Soudijn W. van Galen PJ, et al. Among authors: ijzerman ap. J Med Chem. 1990 Jun;33(6):1708-13. doi: 10.1021/jm00168a027. J Med Chem. 1990. PMID: 2342066

4

Ribose-modified adenosine analogues as potential partial agonists for the adenosine receptor.

van der Wenden EM, von Frijtag Drabbe Künzel JK, Mathôt RA, Danhof M, IJzerman AP, Soudijn W. van der Wenden EM, et al. Among authors: ijzerman ap. J Med Chem. 1995 Sep 29;38(20):4000-6. doi: 10.1021/jm00020a014. J Med Chem. 1995. PMID: 7562934

5

Modelling of the pharmacodynamic interaction of an A1 adenosine receptor agonist and antagonist in vivo: N6-cyclopentyladenosine and 8-cyclopentyltheophylline.

Appel S, Mathôt RA, Langemeijer MW, IJzerman AP, Danhof M. Appel S, et al. Among authors: ijzerman ap. Br J Pharmacol. 1995 Aug;115(7):1253-9. doi: 10.1111/j.1476-5381.1995.tb15033.x. Br J Pharmacol. 1995. PMID: 7582553 Free PMC article.

6

8-substituted adenosine and theophylline-7-riboside analogues as potential partial agonists for the adenosine A1 receptor.

Van der Wenden EM, Hartog-Witte HR, Roelen HC, von Frijtag Drabbe Künzel JK, Pirovano IM, Mathôt RA, Danhof M, Van Aerschot A, Lidaks MJ, IJzerman AP, et al. Van der Wenden EM, et al. Among authors: ijzerman ap. Eur J Pharmacol. 1995 Aug 15;290(3):189-99. doi: 10.1016/0922-4106(95)00064-x. Eur J Pharmacol. 1995. PMID: 7589213

7

Partial agonism of theophylline-7-riboside on adenosine receptors.

IJzerman AP, van der Wenden EM, von Frijtag Drabbe Künzel JK, Mathôt RA, Danhof M, Borea PA, Varani K. IJzerman AP, et al. Naunyn Schmiedebergs Arch Pharmacol. 1994 Dec;350(6):638-45. doi: 10.1007/BF00169369. Naunyn Schmiedebergs Arch Pharmacol. 1994. PMID: 7708121

8

Relative binding orientations of adenosine A1 receptor ligands--a test case for Distributed Multipole Analysis in medicinal chemistry.

van der Wenden EM, Price SL, Apaya RP, IJzerman AP, Soudijn W. van der Wenden EM, et al. Among authors: ijzerman ap. J Comput Aided Mol Des. 1995 Feb;9(1):44-54. doi: 10.1007/BF00117277. J Comput Aided Mol Des. 1995. PMID: 7751869

9

Molecular modeling of adenosine receptors. The ligand binding site on the rat adenosine A2A receptor.

IJzerman AP, van der Wenden EM, van Galen PJ, Jacobson KA. IJzerman AP, et al. Eur J Pharmacol. 1994 Jun 15;268(1):95-104. doi: 10.1016/0922-4106(94)90124-4. Eur J Pharmacol. 1994. PMID: 7925617 Free PMC article.

10

Assessment of the enantiomeric purity of R- and S-N6-phenylisopropyladenosine (PIA): implications for adenosine receptor subclassification.

Mathôt RA, Van den Aarsen BC, von Frijtag Drabble Künzel JK, Danhof M, Ijzerman AP. Mathôt RA, et al. Among authors: ijzerman ap. Naunyn Schmiedebergs Arch Pharmacol. 1994 Jul;350(1):109-12. doi: 10.1007/BF00180020. Naunyn Schmiedebergs Arch Pharmacol. 1994. PMID: 7935848

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