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Unveiling the Antiviral Capabilities of Targeting Human Dihydroorotate Dehydrogenase against SARS-CoV-2.
Purificação AD, Silva-Mendonça S, Cruz LV, Sacramento CQ, Temerozo JR, Fintelman-Rodrigues N, de Freitas CS, Godoi BF, Vaidergorn MM, Leite JA, Salazar Alvarez LC, Freitas MV, Silvac MFB, Martin BA, Lopez RFV, Neves BJ, Costa FTM, Souza TML, da Silva Emery F, Andrade CH, Nonato MC. Purificação AD, et al. Among authors: sacramento cq. ACS Omega. 2024 Feb 28;9(10):11418-11430. doi: 10.1021/acsomega.3c07845. eCollection 2024 Mar 12. ACS Omega. 2024. PMID: 38496952 Free PMC article.
Multilayer microparticles for programmed sequential release of phenolic compounds from Eugenia stipitata: Stability and bioavailability.
Queiroz de Oliveira W, Angélica Neri Numa I, Alvim ID, Azeredo HMC, Santos LB, Borsoi FT, de Araújo FF, Sawaya ACHF, do Nascimento GC, Clerici MTPS, do Sacramento CK, Maria Pastore G. Queiroz de Oliveira W, et al. Among authors: do sacramento ck. Food Chem. 2024 Jun 15;443:138579. doi: 10.1016/j.foodchem.2024.138579. Epub 2024 Jan 26. Food Chem. 2024. PMID: 38301560
AAV-Mediated Delivery of Plakophilin-2a Arrests Progression of Arrhythmogenic Right Ventricular Cardiomyopathy in Murine Hearts: Preclinical Evidence Supporting Gene Therapy in Humans.
van Opbergen CJM, Narayanan B, Sacramento CB, Stiles KM, Mishra V, Frenk E, Ricks D, Chen G, Zhang M, Yarabe P, Schwartz J, Delmar M, Herzog CD, Cerrone M. van Opbergen CJM, et al. Among authors: sacramento cb. Circ Genom Precis Med. 2024 Feb;17(1):e004305. doi: 10.1161/CIRCGEN.123.004305. Epub 2024 Jan 30. Circ Genom Precis Med. 2024. PMID: 38288614 Free article.
Inhibition of the SREBP pathway prevents SARS-CoV-2 replication and inflammasome activation.
Soares VC, Dias SSG, Santos JC, Azevedo-Quintanilha IG, Moreira IBG, Sacramento CQ, Fintelman-Rodrigues N, Temerozo JR, da Silva MAN, Barreto-Vieira DF, Souza TM, Bozza PT. Soares VC, et al. Among authors: sacramento cq. Life Sci Alliance. 2023 Sep 5;6(11):e202302049. doi: 10.26508/lsa.202302049. Print 2023 Nov. Life Sci Alliance. 2023. PMID: 37669865 Free PMC article.
Boosting Titanium Surfaces with Positive Charges: Newly Developed Cationic Coating Combines Anticorrosive and Bactericidal Properties for Implant Application.
Silva JPDS, Costa RC, Nagay BE, Borges MHR, Sacramento CM, da Cruz NC, Rangel EC, Fortulan CA, da Silva JHD, Ruiz KGS, Barão VAR. Silva JPDS, et al. Among authors: sacramento cm. ACS Biomater Sci Eng. 2023 Sep 11;9(9):5389-5404. doi: 10.1021/acsbiomaterials.3c00491. Epub 2023 Aug 10. ACS Biomater Sci Eng. 2023. PMID: 37561763
Severe influenza infection is associated with inflammatory programmed cell death in infected macrophages.
Ferreira AC, Sacramento CQ, Pereira-Dutra FS, Fintelman-Rodrigues N, Silva PP, Mattos M, de Freitas CS, Marttorelli A, de Melo GR, Campos MM, Azevedo-Quintanilha IG, Carlos AS, Emídio JV, Garcia CC, Bozza PT, Bozza FA, Souza TML. Ferreira AC, et al. Among authors: sacramento cq. Front Cell Infect Microbiol. 2023 Feb 16;13:1067285. doi: 10.3389/fcimb.2023.1067285. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 36875528 Free PMC article.
Preclinical development of kinetin as a safe error-prone SARS-CoV-2 antiviral able to attenuate virus-induced inflammation.
Souza TML, Pinho VD, Setim CF, Sacramento CQ, Marcon R, Fintelman-Rodrigues N, Chaves OA, Heller M, Temerozo JR, Ferreira AC, Mattos M, Momo PB, Dias SSG, Gesto JSM, Pereira-Dutra F, Viola JPB, Queiroz-Junior CM, Guimarães LC, Chaves IM, Guimarães PPG, Costa VV, Teixeira MM, Bou-Habib DC, Bozza PT, Aguillón AR, Siqueira-Junior J, Macedo-Junior S, Andrade EL, Fadanni GP, Tolouei SEL, Potrich FB, Santos AA, Marques NF, Calixto JB, Rabi JA. Souza TML, et al. Among authors: sacramento cq. Nat Commun. 2023 Jan 13;14(1):199. doi: 10.1038/s41467-023-35928-z. Nat Commun. 2023. PMID: 36639383 Free PMC article.
Dengue induces iNOS expression and nitric oxide synthesis in platelets through IL-1R.
Pinheiro MBM, Rozini SV, Quirino-Teixeira AC, Barbosa-Lima G, Lopes JF, Sacramento CQ, Bozza FA, Bozza PT, Hottz ED. Pinheiro MBM, et al. Among authors: sacramento cq. Front Immunol. 2022 Dec 7;13:1029213. doi: 10.3389/fimmu.2022.1029213. eCollection 2022. Front Immunol. 2022. PMID: 36569864 Free PMC article.
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