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Identification of novel drug-resistant EGFR mutant inhibitors by in silico screening using comprehensive assessments of protein structures.
Sato T, Watanabe H, Tsuganezawa K, Yuki H, Mikuni J, Yoshikawa S, Kukimoto-Niino M, Fujimoto T, Terazawa Y, Wakiyama M, Kojima H, Okabe T, Nagano T, Shirouzu M, Yokoyama S, Tanaka A, Honma T. Sato T, et al. Bioorg Med Chem. 2012 Jun 15;20(12):3756-67. doi: 10.1016/j.bmc.2012.04.042. Epub 2012 Apr 27. Bioorg Med Chem. 2012. PMID: 22607878
Crystal structures of possible lysine decarboxylases from Thermus thermophilus HB8.
Kukimoto-Niino M, Murayama K, Kato-Murayama M, Idaka M, Bessho Y, Tatsuguchi A, Ushikoshi-Nakayama R, Terada T, Kuramitsu S, Shirouzu M, Yokoyama S. Kukimoto-Niino M, et al. Protein Sci. 2004 Nov;13(11):3038-42. doi: 10.1110/ps.041012404. Epub 2004 Sep 30. Protein Sci. 2004. PMID: 15459330 Free PMC article.
Crystal structure of the RUN domain of the RAP2-interacting protein x.
Kukimoto-Niino M, Takagi T, Akasaka R, Murayama K, Uchikubo-Kamo T, Terada T, Inoue M, Watanabe S, Tanaka A, Hayashizaki Y, Kigawa T, Shirouzu M, Yokoyama S. Kukimoto-Niino M, et al. J Biol Chem. 2006 Oct 20;281(42):31843-53. doi: 10.1074/jbc.M604960200. Epub 2006 Aug 23. J Biol Chem. 2006. PMID: 16928684 Free article.
Structure of the UNC5H2 death domain.
Handa N, Kukimoto-Niino M, Akasaka R, Murayama K, Terada T, Inoue M, Yabuki T, Aoki M, Seki E, Matsuda T, Nunokawa E, Tanaka A, Hayashizaki Y, Kigawa T, Shirouzu M, Yokoyama S. Handa N, et al. Acta Crystallogr D Biol Crystallogr. 2006 Dec;62(Pt 12):1502-9. doi: 10.1107/S0907444906039369. Epub 2006 Nov 23. Acta Crystallogr D Biol Crystallogr. 2006. PMID: 17139086
54 results