Baumann K - Search Results

1

2-Anilino-4-(benzimidazol-2-yl)pyrimidines--a multikinase inhibitor scaffold with antiproliferative activity toward cancer cell lines.

Determann R, Dreher J, Baumann K, Preu L, Jones PG, Totzke F, Schächtele C, Kubbutat MH, Kunick C. Determann R, et al. Among authors: baumann k. Eur J Med Chem. 2012 Jul;53:254-63. doi: 10.1016/j.ejmech.2012.04.007. Epub 2012 Apr 14. Eur J Med Chem. 2012. PMID: 22560627

2

10-iodo-11H-indolo[3,2-c]quinoline-6-carboxylic acids are selective inhibitors of DYRK1A.

Falke H, Chaikuad A, Becker A, Loaëc N, Lozach O, Abu Jhaisha S, Becker W, Jones PG, Preu L, Baumann K, Knapp S, Meijer L, Kunick C. Falke H, et al. Among authors: baumann k. J Med Chem. 2015 Apr 9;58(7):3131-43. doi: 10.1021/jm501994d. Epub 2015 Mar 23. J Med Chem. 2015. PMID: 25730262 Free PMC article.

3

Identification of 2-anilino-9-methoxy-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepin-6-ones as dual PLK1/VEGF-R2 kinase inhibitor chemotypes by structure-based lead generation.

Egert-Schmidt AM, Dreher J, Dunkel U, Kohfeld S, Preu L, Weber H, Ehlert JE, Mutschler B, Totzke F, Schächtele C, Kubbutat MH, Baumann K, Kunick C. Egert-Schmidt AM, et al. Among authors: baumann k. J Med Chem. 2010 Mar 25;53(6):2433-42. doi: 10.1021/jm901388c. J Med Chem. 2010. PMID: 20170163

4

QSAR guided synthesis of simplified antiplasmodial analogs of naphthylisoquinoline alkaloids.

Bringmann G, Bischof SK, Müller S, Gulder T, Winter C, Stich A, Moll H, Kaiser M, Brun R, Dreher J, Baumann K. Bringmann G, et al. Among authors: baumann k. Eur J Med Chem. 2010 Nov;45(11):5370-83. doi: 10.1016/j.ejmech.2010.08.062. Epub 2010 Sep 17. Eur J Med Chem. 2010. PMID: 20850207

5

xMaP-An Interpretable Alignment-Free Four-Dimensional Quantitative Structure-Activity Relationship Technique Based on Molecular Surface Properties and Conformer Ensembles.

Dreher J, Scheiber J, Stiefl N, Baumann K. Dreher J, et al. Among authors: baumann k. J Chem Inf Model. 2018 Jan 22;58(1):165-181. doi: 10.1021/acs.jcim.7b00419. Epub 2018 Jan 2. J Chem Inf Model. 2018. PMID: 29172519

6

Synthesis and acetylcholinesterase inhibition of 5-desamino huperzine A derivatives.

Högenauer K, Baumann K, Enz A, Mulzer J. Högenauer K, et al. Among authors: baumann k. Bioorg Med Chem Lett. 2001 Oct 8;11(19):2627-30. doi: 10.1016/s0960-894x(01)00518-2. Bioorg Med Chem Lett. 2001. PMID: 11551765

7

A small-molecule inhibitor of Nipah virus envelope protein-mediated membrane fusion.

Niedermeier S, Singethan K, Rohrer SG, Matz M, Kossner M, Diederich S, Maisner A, Schmitz J, Hiltensperger G, Baumann K, Holzgrabe U, Schneider-Schaulies J. Niedermeier S, et al. Among authors: baumann k. J Med Chem. 2009 Jul 23;52(14):4257-65. doi: 10.1021/jm900411s. J Med Chem. 2009. PMID: 19499921

8

From catalysts to bioactive organometallics: do Grubbs catalysts trigger biological effects?

Oehninger L, Alborzinia H, Ludewig S, Baumann K, Wölfl S, Ott I. Oehninger L, et al. Among authors: baumann k. ChemMedChem. 2011 Dec 9;6(12):2142-5. doi: 10.1002/cmdc.201100308. Epub 2011 Sep 7. ChemMedChem. 2011. PMID: 21901835 No abstract available.

9

A gold(i) biscarbene complex with improved activity as a TrxR inhibitor and cytotoxic drug: comparative studies with different gold metallodrugs.

Schmidt C, Albrecht L, Balasupramaniam S, Misgeld R, Karge B, Brönstrup M, Prokop A, Baumann K, Reichl S, Ott I. Schmidt C, et al. Among authors: baumann k. Metallomics. 2019 Mar 20;11(3):533-545. doi: 10.1039/c8mt00306h. Metallomics. 2019. PMID: 30516775

10

A new lead for nonpeptidic active-site-directed inhibitors of the severe acute respiratory syndrome coronavirus main protease discovered by a combination of screening and docking methods.

Kaeppler U, Stiefl N, Schiller M, Vicik R, Breuning A, Schmitz W, Rupprecht D, Schmuck C, Baumann K, Ziebuhr J, Schirmeister T. Kaeppler U, et al. Among authors: baumann k. J Med Chem. 2005 Nov 3;48(22):6832-42. doi: 10.1021/jm0501782. J Med Chem. 2005. PMID: 16250642

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