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A novel sulindac derivative that potently suppresses colon tumor cell growth by inhibiting cGMP phosphodiesterase and β-catenin transcriptional activity.
Whitt JD, Li N, Tinsley HN, Chen X, Zhang W, Li Y, Gary BD, Keeton AB, Xi Y, Abadi AH, Grizzle WE, Piazza GA. Whitt JD, et al. Among authors: zhang w. Cancer Prev Res (Phila). 2012 Jun;5(6):822-33. doi: 10.1158/1940-6207.CAPR-11-0559. Epub 2012 May 3. Cancer Prev Res (Phila). 2012. PMID: 22556201 Free PMC article.
Frizzled7 as an emerging target for cancer therapy.
King TD, Zhang W, Suto MJ, Li Y. King TD, et al. Among authors: zhang w. Cell Signal. 2012 Apr;24(4):846-51. doi: 10.1016/j.cellsig.2011.12.009. Epub 2011 Dec 13. Cell Signal. 2012. PMID: 22182510 Free PMC article. Review.
KIFC1 is a novel potential therapeutic target for breast cancer.
Li Y, Lu W, Chen D, Boohaker RJ, Zhai L, Padmalayam I, Wennerberg K, Xu B, Zhang W. Li Y, et al. Among authors: zhang w. Cancer Biol Ther. 2015;16(9):1316-22. doi: 10.1080/15384047.2015.1070980. Epub 2015 Jul 15. Cancer Biol Ther. 2015. PMID: 26177331 Free PMC article.
Discovery of a novel inhibitor of kinesin-like protein KIFC1.
Zhang W, Zhai L, Wang Y, Boohaker RJ, Lu W, Gupta VV, Padmalayam I, Bostwick RJ, White EL, Ross LJ, Maddry J, Ananthan S, Augelli-Szafran CE, Suto MJ, Xu B, Li R, Li Y. Zhang W, et al. Biochem J. 2016 Apr 15;473(8):1027-35. doi: 10.1042/BJ20150992. Epub 2016 Feb 4. Biochem J. 2016. PMID: 26846349 Free PMC article.
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