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Plasmalogens inhibit APP processing by directly affecting γ-secretase activity in Alzheimer's disease.
ScientificWorldJournal. 2012;2012:141240. doi: 10.1100/2012/141240. Epub 2012 Apr 1.
ScientificWorldJournal. 2012.
PMID: 22547976
Free PMC article.
Plasmalogen synthesis is regulated via alkyl-dihydroxyacetonephosphate-synthase by amyloid precursor protein processing and is affected in Alzheimer's disease.
Grimm MO, Kuchenbecker J, Rothhaar TL, Grösgen S, Hundsdörfer B, Burg VK, Friess P, Müller U, Grimm HS, Riemenschneider M, Hartmann T.
Grimm MO, et al. Among authors: burg vk.
J Neurochem. 2011 Mar;116(5):916-25. doi: 10.1111/j.1471-4159.2010.07070.x. Epub 2011 Jan 12.
J Neurochem. 2011.
PMID: 21214572
Free article.
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Trans fatty acids enhance amyloidogenic processing of the Alzheimer amyloid precursor protein (APP).
Grimm MO, Rothhaar TL, Grösgen S, Burg VK, Hundsdörfer B, Haupenthal VJ, Friess P, Kins S, Grimm HS, Hartmann T.
Grimm MO, et al. Among authors: burg vk.
J Nutr Biochem. 2012 Oct;23(10):1214-23. doi: 10.1016/j.jnutbio.2011.06.015. Epub 2011 Dec 29.
J Nutr Biochem. 2012.
PMID: 22209004
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Amyloid precursor protein (APP) mediated regulation of ganglioside homeostasis linking Alzheimer's disease pathology with ganglioside metabolism.
Grimm MO, Zinser EG, Grösgen S, Hundsdörfer B, Rothhaar TL, Burg VK, Kaestner L, Bayer TA, Lipp P, Müller U, Grimm HS, Hartmann T.
Grimm MO, et al. Among authors: burg vk.
PLoS One. 2012;7(3):e34095. doi: 10.1371/journal.pone.0034095. Epub 2012 Mar 28.
PLoS One. 2012.
PMID: 22470521
Free PMC article.
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Plant sterols the better cholesterol in Alzheimer's disease? A mechanistical study.
Burg VK, Grimm HS, Rothhaar TL, Grösgen S, Hundsdörfer B, Haupenthal VJ, Zimmer VC, Mett J, Weingärtner O, Laufs U, Broersen LM, Tanila H, Vanmierlo T, Lütjohann D, Hartmann T, Grimm MO.
Burg VK, et al.
J Neurosci. 2013 Oct 9;33(41):16072-87. doi: 10.1523/JNEUROSCI.1506-13.2013.
J Neurosci. 2013.
PMID: 24107941
Free PMC article.
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Docosahexaenoic acid reduces amyloid beta production via multiple pleiotropic mechanisms.
Grimm MO, Kuchenbecker J, Grösgen S, Burg VK, Hundsdörfer B, Rothhaar TL, Friess P, de Wilde MC, Broersen LM, Penke B, Péter M, Vígh L, Grimm HS, Hartmann T.
Grimm MO, et al. Among authors: burg vk.
J Biol Chem. 2011 Apr 22;286(16):14028-39. doi: 10.1074/jbc.M110.182329. Epub 2011 Feb 15.
J Biol Chem. 2011.
PMID: 21324907
Free PMC article.
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Intracellular APP Domain Regulates Serine-Palmitoyl-CoA Transferase Expression and Is Affected in Alzheimer's Disease.
Grimm MO, Grösgen S, Rothhaar TL, Burg VK, Hundsdörfer B, Haupenthal VJ, Friess P, Müller U, Fassbender K, Riemenschneider M, Grimm HS, Hartmann T.
Grimm MO, et al. Among authors: burg vk.
Int J Alzheimers Dis. 2011;2011:695413. doi: 10.4061/2011/695413. Epub 2011 May 18.
Int J Alzheimers Dis. 2011.
PMID: 21660213
Free PMC article.
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