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Plasmalogen synthesis is regulated via alkyl-dihydroxyacetonephosphate-synthase by amyloid precursor protein processing and is affected in Alzheimer's disease.
Grimm MO, Kuchenbecker J, Rothhaar TL, Grösgen S, Hundsdörfer B, Burg VK, Friess P, Müller U, Grimm HS, Riemenschneider M, Hartmann T. Grimm MO, et al. Among authors: burg vk. J Neurochem. 2011 Mar;116(5):916-25. doi: 10.1111/j.1471-4159.2010.07070.x. Epub 2011 Jan 12. J Neurochem. 2011. PMID: 21214572 Free article.
Plant sterols the better cholesterol in Alzheimer's disease? A mechanistical study.
Burg VK, Grimm HS, Rothhaar TL, Grösgen S, Hundsdörfer B, Haupenthal VJ, Zimmer VC, Mett J, Weingärtner O, Laufs U, Broersen LM, Tanila H, Vanmierlo T, Lütjohann D, Hartmann T, Grimm MO. Burg VK, et al. J Neurosci. 2013 Oct 9;33(41):16072-87. doi: 10.1523/JNEUROSCI.1506-13.2013. J Neurosci. 2013. PMID: 24107941 Free PMC article.
Docosahexaenoic acid reduces amyloid beta production via multiple pleiotropic mechanisms.
Grimm MO, Kuchenbecker J, Grösgen S, Burg VK, Hundsdörfer B, Rothhaar TL, Friess P, de Wilde MC, Broersen LM, Penke B, Péter M, Vígh L, Grimm HS, Hartmann T. Grimm MO, et al. Among authors: burg vk. J Biol Chem. 2011 Apr 22;286(16):14028-39. doi: 10.1074/jbc.M110.182329. Epub 2011 Feb 15. J Biol Chem. 2011. PMID: 21324907 Free PMC article.