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The magnitude of HIV-1 resistance to the CCR5 antagonist maraviroc may impart a differential alteration in HIV-1 tropism for macrophages and T-cell subsets.
Flynn JK, Paukovics G, Moore MS, Ellett A, Gray LR, Duncan R, Salimi H, Jubb B, Westby M, Purcell DF, Lewin SR, Lee B, Churchill MJ, Gorry PR, Roche M. Flynn JK, et al. Among authors: gray lr. Virology. 2013 Jul 20;442(1):51-8. doi: 10.1016/j.virol.2013.03.026. Epub 2013 Apr 17. Virology. 2013. PMID: 23602007 Free article.
A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations.
Roche M, Salimi H, Duncan R, Wilkinson BL, Chikere K, Moore MS, Webb NE, Zappi H, Sterjovski J, Flynn JK, Ellett A, Gray LR, Lee B, Jubb B, Westby M, Ramsland PA, Lewin SR, Payne RJ, Churchill MJ, Gorry PR. Roche M, et al. Among authors: gray lr. Retrovirology. 2013 Apr 20;10:43. doi: 10.1186/1742-4690-10-43. Retrovirology. 2013. PMID: 23602046 Free PMC article.
Ex vivo response to histone deacetylase (HDAC) inhibitors of the HIV long terminal repeat (LTR) derived from HIV-infected patients on antiretroviral therapy.
Lu HK, Gray LR, Wightman F, Ellenberg P, Khoury G, Cheng WJ, Mota TM, Wesselingh S, Gorry PR, Cameron PU, Churchill MJ, Lewin SR. Lu HK, et al. Among authors: gray lr. PLoS One. 2014 Nov 19;9(11):e113341. doi: 10.1371/journal.pone.0113341. eCollection 2014. PLoS One. 2014. PMID: 25409334 Free PMC article.
Inhibition of catechol-O-methyl transferase (COMT) by tolcapone restores reductions in microtubule-associated protein 2 (MAP2) and synaptophysin (SYP) following exposure of neuronal cells to neurotropic HIV.
Lee TT, Chana G, Gorry PR, Ellett A, Bousman CA, Churchill MJ, Gray LR, Everall IP. Lee TT, et al. Among authors: gray lr. J Neurovirol. 2015 Oct;21(5):535-43. doi: 10.1007/s13365-015-0354-y. Epub 2015 Jun 3. J Neurovirol. 2015. PMID: 26037113 Free PMC article.
75 results