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A new class of highly potent matrix metalloproteinase inhibitors based on triazole-substituted hydroxamates: (radio)synthesis and in vitro and first in vivo evaluation.
Hugenberg V, Breyholz HJ, Riemann B, Hermann S, Schober O, Schäfers M, Gangadharmath U, Mocharla V, Kolb H, Walsh J, Zhang W, Kopka K, Wagner S. Hugenberg V, et al. Among authors: walsh j. J Med Chem. 2012 May 24;55(10):4714-27. doi: 10.1021/jm300199g. Epub 2012 May 16. J Med Chem. 2012. PMID: 22540974
Inverse 1,2,3-triazole-1-yl-ethyl substituted hydroxamates as highly potent matrix metalloproteinase inhibitors: (radio)synthesis, in vitro and first in vivo evaluation.
Hugenberg V, Riemann B, Hermann S, Schober O, Schäfers M, Szardenings K, Lebedev A, Gangadharmath U, Kolb H, Walsh J, Zhang W, Kopka K, Wagner S. Hugenberg V, et al. Among authors: walsh j. J Med Chem. 2013 Sep 12;56(17):6858-70. doi: 10.1021/jm4006753. Epub 2013 Aug 16. J Med Chem. 2013. PMID: 23899323
Synthesis, radiosynthesis, in vitro and first in vivo evaluation of a new matrix metalloproteinase inhibitor based on γ-fluorinated α-sulfonylaminohydroxamic acid.
Hugenberg V, Behrends M, Wagner S, Hermann S, Schäfers M, Kolb HC, Szardenings K, Walsh JC, Gomez LF, Kopka K, Haufe G. Hugenberg V, et al. EJNMMI Radiopharm Chem. 2018 Jul 27;3:10. doi: 10.1186/s41181-018-0045-0. eCollection 2018 Dec. EJNMMI Radiopharm Chem. 2018. PMID: 30101186 Free PMC article.
Evaluation of [(18)F]-CP18 as a PET imaging tracer for apoptosis.
Su H, Chen G, Gangadharmath U, Gomez LF, Liang Q, Mu F, Mocharla VP, Szardenings AK, Walsh JC, Xia CF, Yu C, Kolb HC. Su H, et al. Mol Imaging Biol. 2013 Dec;15(6):739-47. doi: 10.1007/s11307-013-0644-9. Mol Imaging Biol. 2013. PMID: 23681757
[(18)F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease.
Xia CF, Arteaga J, Chen G, Gangadharmath U, Gomez LF, Kasi D, Lam C, Liang Q, Liu C, Mocharla VP, Mu F, Sinha A, Su H, Szardenings AK, Walsh JC, Wang E, Yu C, Zhang W, Zhao T, Kolb HC. Xia CF, et al. Among authors: walsh jc. Alzheimers Dement. 2013 Nov;9(6):666-76. doi: 10.1016/j.jalz.2012.11.008. Epub 2013 Feb 12. Alzheimers Dement. 2013. PMID: 23411393
A highly selective and specific PET tracer for imaging of tau pathologies.
Zhang W, Arteaga J, Cashion DK, Chen G, Gangadharmath U, Gomez LF, Kasi D, Lam C, Liang Q, Liu C, Mocharla VP, Mu F, Sinha A, Szardenings AK, Wang E, Walsh JC, Xia C, Yu C, Zhao T, Kolb HC. Zhang W, et al. Among authors: walsh jc. J Alzheimers Dis. 2012;31(3):601-12. doi: 10.3233/JAD-2012-120712. J Alzheimers Dis. 2012. PMID: 22683529
5,875 results