Deng HX - Search Results

1

Iron accumulation in deep cortical layers accounts for MRI signal abnormalities in ALS: correlating 7 tesla MRI and pathology.

Kwan JY, Jeong SY, Van Gelderen P, Deng HX, Quezado MM, Danielian LE, Butman JA, Chen L, Bayat E, Russell J, Siddique T, Duyn JH, Rouault TA, Floeter MK. Kwan JY, et al. Among authors: deng hx. PLoS One. 2012;7(4):e35241. doi: 10.1371/journal.pone.0035241. Epub 2012 Apr 17. PLoS One. 2012. PMID: 22529995 Free PMC article. Clinical Trial.

2

A novel ALS-associated variant in UBQLN4 regulates motor axon morphogenesis.

Edens BM, Yan J, Miller N, Deng HX, Siddique T, Ma YC. Edens BM, et al. Among authors: deng hx. Elife. 2017 May 2;6:e25453. doi: 10.7554/eLife.25453. Elife. 2017. PMID: 28463112 Free PMC article.

3

Disulfide cross-linked protein represents a significant fraction of ALS-associated Cu, Zn-superoxide dismutase aggregates in spinal cords of model mice.

Furukawa Y, Fu R, Deng HX, Siddique T, O'Halloran TV. Furukawa Y, et al. Among authors: deng hx. Proc Natl Acad Sci U S A. 2006 May 2;103(18):7148-53. doi: 10.1073/pnas.0602048103. Epub 2006 Apr 24. Proc Natl Acad Sci U S A. 2006. PMID: 16636274 Free PMC article.

4

Restricted expression of mutant SOD1 in spinal motor neurons and interneurons induces motor neuron pathology.

Wang L, Sharma K, Deng HX, Siddique T, Grisotti G, Liu E, Roos RP. Wang L, et al. Among authors: deng hx. Neurobiol Dis. 2008 Mar;29(3):400-8. doi: 10.1016/j.nbd.2007.10.004. Epub 2007 Oct 23. Neurobiol Dis. 2008. PMID: 18054242

5

Wild-type SOD1 overexpression accelerates disease onset of a G85R SOD1 mouse.

Wang L, Deng HX, Grisotti G, Zhai H, Siddique T, Roos RP. Wang L, et al. Among authors: deng hx. Hum Mol Genet. 2009 May 1;18(9):1642-51. doi: 10.1093/hmg/ddp085. Epub 2009 Feb 19. Hum Mol Genet. 2009. PMID: 19233858 Free PMC article.

6

Alzheimer disease and amyotrophic lateral sclerosis: an etiopathogenic connection.

Wang X, Blanchard J, Grundke-Iqbal I, Wegiel J, Deng HX, Siddique T, Iqbal K. Wang X, et al. Among authors: deng hx. Acta Neuropathol. 2014 Feb;127(2):243-56. doi: 10.1007/s00401-013-1175-9. Epub 2013 Oct 18. Acta Neuropathol. 2014. PMID: 24136402 Free PMC article.

7

Nuclear export of misfolded SOD1 mediated by a normally buried NES-like sequence reduces proteotoxicity in the nucleus.

Zhong Y, Wang J, Henderson MJ, Yang P, Hagen BM, Siddique T, Vogel BE, Deng HX, Fang S. Zhong Y, et al. Among authors: deng hx. Elife. 2017 May 2;6:e23759. doi: 10.7554/eLife.23759. Elife. 2017. PMID: 28463106 Free PMC article.

8

Distal axonopathy in an alsin-deficient mouse model.

Deng HX, Zhai H, Fu R, Shi Y, Gorrie GH, Yang Y, Liu E, Dal Canto MC, Mugnaini E, Siddique T. Deng HX, et al. Hum Mol Genet. 2007 Dec 1;16(23):2911-20. doi: 10.1093/hmg/ddm251. Epub 2007 Sep 12. Hum Mol Genet. 2007. PMID: 17855450

9

Hyperactive intracellular calcium signaling associated with localized mitochondrial defects in skeletal muscle of an animal model of amyotrophic lateral sclerosis.

Zhou J, Yi J, Fu R, Liu E, Siddique T, Ríos E, Deng HX. Zhou J, et al. Among authors: deng hx. J Biol Chem. 2010 Jan 1;285(1):705-12. doi: 10.1074/jbc.M109.041319. Epub 2009 Nov 4. J Biol Chem. 2010. PMID: 19889637 Free PMC article.

10

SQSTM1 mutations in familial and sporadic amyotrophic lateral sclerosis.

Fecto F, Yan J, Vemula SP, Liu E, Yang Y, Chen W, Zheng JG, Shi Y, Siddique N, Arrat H, Donkervoort S, Ajroud-Driss S, Sufit RL, Heller SL, Deng HX, Siddique T. Fecto F, et al. Among authors: deng hx. Arch Neurol. 2011 Nov;68(11):1440-6. doi: 10.1001/archneurol.2011.250. Arch Neurol. 2011. PMID: 22084127

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