Georgiou G - Search Results

1

Structure-based design of supercharged, highly thermoresistant antibodies.

Miklos AE, Kluwe C, Der BS, Pai S, Sircar A, Hughes RA, Berrondo M, Xu J, Codrea V, Buckley PE, Calm AM, Welsh HS, Warner CR, Zacharko MA, Carney JP, Gray JJ, Georgiou G, Kuhlman B, Ellington AD. Miklos AE, et al. Among authors: georgiou g. Chem Biol. 2012 Apr 20;19(4):449-55. doi: 10.1016/j.chembiol.2012.01.018. Chem Biol. 2012. PMID: 22520751 Free PMC article.

2

Automated selection of aptamers against protein targets translated in vitro: from gene to aptamer.

Cox JC, Hayhurst A, Hesselberth J, Bayer TS, Georgiou G, Ellington AD. Cox JC, et al. Among authors: georgiou g. Nucleic Acids Res. 2002 Oct 15;30(20):e108. doi: 10.1093/nar/gnf107. Nucleic Acids Res. 2002. PMID: 12384610 Free PMC article.

3

Bacterial biosynthesis of cadmium sulfide nanocrystals.

Sweeney RY, Mao C, Gao X, Burt JL, Belcher AM, Georgiou G, Iverson BL. Sweeney RY, et al. Among authors: georgiou g. Chem Biol. 2004 Nov;11(11):1553-9. doi: 10.1016/j.chembiol.2004.08.022. Chem Biol. 2004. PMID: 15556006

4

De novo design and evolution of artificial disulfide isomerase enzymes analogous to the bacterial DsbC.

Arredondo S, Segatori L, Gilbert HF, Georgiou G. Arredondo S, et al. Among authors: georgiou g. J Biol Chem. 2008 Nov 14;283(46):31469-76. doi: 10.1074/jbc.M803346200. Epub 2008 Sep 9. J Biol Chem. 2008. PMID: 18782764 Free PMC article.

5

Engineering antibody fragments to fold in the absence of disulfide bonds.

Seo MJ, Jeong KJ, Leysath CE, Ellington AD, Iverson BL, Georgiou G. Seo MJ, et al. Among authors: georgiou g. Protein Sci. 2009 Feb;18(2):259-67. doi: 10.1002/pro.31. Protein Sci. 2009. PMID: 19177559 Free PMC article.

6

Crystal structure of the engineered neutralizing antibody M18 complexed to domain 4 of the anthrax protective antigen.

Leysath CE, Monzingo AF, Maynard JA, Barnett J, Georgiou G, Iverson BL, Robertus JD. Leysath CE, et al. Among authors: georgiou g. J Mol Biol. 2009 Apr 3;387(3):680-93. doi: 10.1016/j.jmb.2009.02.003. Epub 2009 Feb 10. J Mol Biol. 2009. PMID: 19361425 Free PMC article.

7

Rapid construction and characterization of synthetic antibody libraries without DNA amplification.

Ge X, Mazor Y, Hunicke-Smith SP, Ellington AD, Georgiou G. Ge X, et al. Among authors: georgiou g. Biotechnol Bioeng. 2010 Jun 15;106(3):347-57. doi: 10.1002/bit.22712. Biotechnol Bioeng. 2010. PMID: 20198660

8

Monoclonal antibodies isolated without screening by analyzing the variable-gene repertoire of plasma cells.

Reddy ST, Ge X, Miklos AE, Hughes RA, Kang SH, Hoi KH, Chrysostomou C, Hunicke-Smith SP, Iverson BL, Tucker PW, Ellington AD, Georgiou G. Reddy ST, et al. Among authors: georgiou g. Nat Biotechnol. 2010 Sep;28(9):965-9. doi: 10.1038/nbt.1673. Epub 2010 Aug 29. Nat Biotechnol. 2010. PMID: 20802495

9

Antibody repertoires in humanized NOD-scid-IL2Rγ(null) mice and human B cells reveals human-like diversification and tolerance checkpoints in the mouse.

Ippolito GC, Hoi KH, Reddy ST, Carroll SM, Ge X, Rogosch T, Zemlin M, Shultz LD, Ellington AD, Vandenberg CL, Georgiou G. Ippolito GC, et al. Among authors: georgiou g. PLoS One. 2012;7(4):e35497. doi: 10.1371/journal.pone.0035497. Epub 2012 Apr 27. PLoS One. 2012. PMID: 22558161 Free PMC article.

10

SCHEMA-designed variants of human Arginase I and II reveal sequence elements important to stability and catalysis.

Romero PA, Stone E, Lamb C, Chantranupong L, Krause A, Miklos AE, Hughes RA, Fechtel B, Ellington AD, Arnold FH, Georgiou G. Romero PA, et al. Among authors: georgiou g. ACS Synth Biol. 2012 Jun 15;1(6):221-8. doi: 10.1021/sb300014t. ACS Synth Biol. 2012. PMID: 22737599 Free PMC article.

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