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SUMOylation of HNF4α regulates protein stability and hepatocyte function.
Zhou W, Hannoun Z, Jaffray E, Medine CN, Black JR, Greenhough S, Zhu L, Ross JA, Forbes S, Wilmut I, Iredale JP, Hay RT, Hay DC. Zhou W, et al. Among authors: black jr. J Cell Sci. 2012 Aug 1;125(Pt 15):3630-5. doi: 10.1242/jcs.102889. Epub 2012 Apr 14. J Cell Sci. 2012. PMID: 22505616 Free PMC article.
Unbiased screening of polymer libraries to define novel substrates for functional hepatocytes with inducible drug metabolism.
Hay DC, Pernagallo S, Diaz-Mochon JJ, Medine CN, Greenhough S, Hannoun Z, Schrader J, Black JR, Fletcher J, Dalgetty D, Thompson AI, Newsome PN, Forbes SJ, Ross JA, Bradley M, Iredale JP. Hay DC, et al. Among authors: black jr. Stem Cell Res. 2011 Mar;6(2):92-102. doi: 10.1016/j.scr.2010.12.002. Epub 2010 Dec 10. Stem Cell Res. 2011. PMID: 21277274 Free article.
Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling.
Hay DC, Fletcher J, Payne C, Terrace JD, Gallagher RC, Snoeys J, Black JR, Wojtacha D, Samuel K, Hannoun Z, Pryde A, Filippi C, Currie IS, Forbes SJ, Ross JA, Newsome PN, Iredale JP. Hay DC, et al. Among authors: black jr. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12301-6. doi: 10.1073/pnas.0806522105. Epub 2008 Aug 21. Proc Natl Acad Sci U S A. 2008. PMID: 18719101 Free PMC article.
Generation of functional human hepatic endoderm from human induced pluripotent stem cells.
Sullivan GJ, Hay DC, Park IH, Fletcher J, Hannoun Z, Payne CM, Dalgetty D, Black JR, Ross JA, Samuel K, Wang G, Daley GQ, Lee JH, Church GM, Forbes SJ, Iredale JP, Wilmut I. Sullivan GJ, et al. Among authors: black jr. Hepatology. 2010 Jan;51(1):329-35. doi: 10.1002/hep.23335. Hepatology. 2010. PMID: 19877180 Free PMC article.
Developing high-fidelity hepatotoxicity models from pluripotent stem cells.
Medine CN, Lucendo-Villarin B, Storck C, Wang F, Szkolnicka D, Khan F, Pernagallo S, Black JR, Marriage HM, Ross JA, Bradley M, Iredale JP, Flint O, Hay DC. Medine CN, et al. Among authors: black jr. Stem Cells Transl Med. 2013 Jul;2(7):505-9. doi: 10.5966/sctm.2012-0138. Epub 2013 Jun 11. Stem Cells Transl Med. 2013. PMID: 23757504 Free PMC article.
287 results