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Chronic HIV infection affects the expression of the 2 transcription factors required for CD8 T-cell differentiation into cytolytic effectors.
Ribeiro-dos-Santos P, Turnbull EL, Monteiro M, Legrand A, Conrod K, Baalwa J, Pellegrino P, Shaw GM, Williams I, Borrow P, Rocha B. Ribeiro-dos-Santos P, et al. Among authors: williams i. Blood. 2012 May 24;119(21):4928-38. doi: 10.1182/blood-2011-12-395186. Epub 2012 Apr 6. Blood. 2012. PMID: 22490682 Free article.
Loss of DNAM-1 contributes to CD8+ T-cell exhaustion in chronic HIV-1 infection.
Cella M, Presti R, Vermi W, Lavender K, Turnbull E, Ochsenbauer-Jambor C, Kappes JC, Ferrari G, Kessels L, Williams I; CHAVI Clinical Core B; McMichael AJ, Haynes BF, Borrow P, Colonna M; NIAID Center for HIV/AIDS Vaccine Immunology. Cella M, et al. Among authors: williams i. Eur J Immunol. 2010 Apr;40(4):949-54. doi: 10.1002/eji.200940234. Eur J Immunol. 2010. PMID: 20201043 Free PMC article.
Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection.
Ferrari G, Korber B, Goonetilleke N, Liu MK, Turnbull EL, Salazar-Gonzalez JF, Hawkins N, Self S, Watson S, Betts MR, Gay C, McGhee K, Pellegrino P, Williams I, Tomaras GD, Haynes BF, Gray CM, Borrow P, Roederer M, McMichael AJ, Weinhold KJ. Ferrari G, et al. Among authors: williams i. PLoS Pathog. 2011 Feb 10;7(2):e1001273. doi: 10.1371/journal.ppat.1001273. PLoS Pathog. 2011. PMID: 21347345 Free PMC article.
Emergence of a distinct HIV-specific IL-10-producing CD8+ T-cell subset with immunomodulatory functions during chronic HIV-1 infection.
Clutton G, Yang H, Hancock G, Sande N, Holloway C, Angus B, von Delft A, Barnes E, Borrow P, Pellegrino P, Williams I, McMichael A, Dorrell L. Clutton G, et al. Among authors: williams i. Eur J Immunol. 2013 Nov;43(11):2875-85. doi: 10.1002/eji.201343646. Epub 2013 Aug 29. Eur J Immunol. 2013. PMID: 23897063 Free article.
Adaptive Reconfiguration of Natural Killer Cells in HIV-1 Infection.
Peppa D, Pedroza-Pacheco I, Pellegrino P, Williams I, Maini MK, Borrow P. Peppa D, et al. Among authors: williams i. Front Immunol. 2018 Mar 16;9:474. doi: 10.3389/fimmu.2018.00474. eCollection 2018. Front Immunol. 2018. PMID: 29616021 Free PMC article. Clinical Trial.
1,911 results