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The synthetic triterpenoid, CDDO, suppresses alloreactive T cell responses and reduces murine early acute graft-versus-host disease mortality.
Sun K, Li M, Konopleva M, Konoplev S, Stephens LC, Kornblau SM, Frolova O, Wilkins DE, Ma W, Welniak LA, Andreeff M, Murphy WJ. Sun K, et al. Among authors: konoplev s. Biol Blood Marrow Transplant. 2007 May;13(5):521-9. doi: 10.1016/j.bbmt.2006.12.453. Epub 2007 Feb 26. Biol Blood Marrow Transplant. 2007. PMID: 17448911 Free PMC article.
PPARgamma-active triterpenoid CDDO enhances ATRA-induced differentiation in APL.
Tabe Y, Konopleva M, Kondo Y, Contractor R, Tsao T, Konoplev S, Shi Y, Ling X, Watt JC, Tsutsumi-Ishii Y, Ohsaka A, Nagaoka I, Issa JP, Kogan SC, Andreeff M. Tabe Y, et al. Among authors: konoplev s. Cancer Biol Ther. 2007 Dec;6(12):1967-77. doi: 10.4161/cbt.6.12.4982. Epub 2007 Sep 4. Cancer Biol Ther. 2007. PMID: 18075297
Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104.
Benito J, Shi Y, Szymanska B, Carol H, Boehm I, Lu H, Konoplev S, Fang W, Zweidler-McKay PA, Campana D, Borthakur G, Bueso-Ramos C, Shpall E, Thomas DA, Jordan CT, Kantarjian H, Wilson WR, Lock R, Andreeff M, Konopleva M. Benito J, et al. Among authors: konoplev s. PLoS One. 2011;6(8):e23108. doi: 10.1371/journal.pone.0023108. Epub 2011 Aug 11. PLoS One. 2011. PMID: 21853076 Free PMC article.
154 results