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Design and optimization of quinazoline derivatives as melanin concentrating hormone receptor 1 (MCHR1) antagonists.
Sasmal S, Balaji G, Kanna Reddy HR, Balasubrahmanyam D, Srinivas G, Kyasa SK, Sasmal PK, Khanna I, Talwar R, Suresh J, Jadhav VP, Muzeeb S, Shashikumar D, Harinder Reddy K, Sebastian VJ, Frimurer TM, Rist Ø, Elster L, Högberg T. Sasmal S, et al. Among authors: elster l. Bioorg Med Chem Lett. 2012 May 1;22(9):3157-62. doi: 10.1016/j.bmcl.2012.03.050. Epub 2012 Mar 23. Bioorg Med Chem Lett. 2012. PMID: 22487182
Discovery of novel, orally available benzimidazoles as melanin concentrating hormone receptor 1 (MCHR1) antagonists.
Sasmal PK, Sasmal S, Rao PT, Venkatesham B, Roshaiah M, Abbineni C, Khanna I, Jadhav VP, Suresh J, Talwar R, Muzeeb S, Receveur JM, Frimurer TM, Rist Ø, Elster L, Högberg T. Sasmal PK, et al. Among authors: elster l. Bioorg Med Chem Lett. 2010 Sep 15;20(18):5443-8. doi: 10.1016/j.bmcl.2010.07.086. Epub 2010 Jul 29. Bioorg Med Chem Lett. 2010. PMID: 20724156
Design and optimization of quinazoline derivatives as melanin concentrating hormone receptor 1 (MCHR1) antagonists: part 2.
Sasmal S, Balasubrahmanyam D, Kanna Reddy HR, Balaji G, Srinivas G, Cheera S, Abbineni C, Sasmal PK, Khanna I, Sebastian VJ, Jadhav VP, Singh MP, Talwar R, Suresh J, Shashikumar D, Harinder Reddy K, Sihorkar V, Frimurer TM, Rist Ø, Elster L, Högberg T. Sasmal S, et al. Among authors: elster l. Bioorg Med Chem Lett. 2012 May 1;22(9):3163-7. doi: 10.1016/j.bmcl.2012.03.049. Epub 2012 Mar 23. Bioorg Med Chem Lett. 2012. PMID: 22497763
Optimisation of in silico derived 2-aminobenzimidazole hits as unprecedented selective kappa opioid receptor agonists.
Sasmal PK, Krishna CV, Adabala SS, Roshaiah M, Rawoof KA, Thadi E, Sukumar KP, Cheera S, Abbineni C, Rao KV, Prasanthi A, Nijhawan K, Jaleel M, Iyer LR, Chaitanya TK, Tiwari NK, Krishna NL, Potluri V, Khanna I, Frimurer TM, Lückmann M, Rist Ø, Elster L, Högberg T. Sasmal PK, et al. Among authors: elster l. Bioorg Med Chem Lett. 2015 Feb 15;25(4):887-92. doi: 10.1016/j.bmcl.2014.12.064. Epub 2015 Jan 6. Bioorg Med Chem Lett. 2015. PMID: 25599839
Negative modulation of GABAA α5 receptors by RO4938581 attenuates discrete sub-chronic and early postnatal phencyclidine (PCP)-induced cognitive deficits in rats.
Redrobe JP, Elster L, Frederiksen K, Bundgaard C, de Jong IE, Smith GP, Bruun AT, Larsen PH, Didriksen M. Redrobe JP, et al. Among authors: elster l. Psychopharmacology (Berl). 2012 Jun;221(3):451-68. doi: 10.1007/s00213-011-2593-9. Epub 2011 Nov 29. Psychopharmacology (Berl). 2012. PMID: 22124672
27 results