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Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity.
Paulk NK, Pekrun K, Zhu E, Nygaard S, Li B, Xu J, Chu K, Leborgne C, Dane AP, Haft A, Zhang Y, Zhang F, Morton C, Valentine MB, Davidoff AM, Nathwani AC, Mingozzi F, Grompe M, Alexander IE, Lisowski L, Kay MA. Paulk NK, et al. Mol Ther. 2018 Jan 3;26(1):289-303. doi: 10.1016/j.ymthe.2017.09.021. Epub 2017 Sep 25. Mol Ther. 2018. PMID: 29055620 Free PMC article.
Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice.
Azuma H, Paulk N, Ranade A, Dorrell C, Al-Dhalimy M, Ellis E, Strom S, Kay MA, Finegold M, Grompe M. Azuma H, et al. Nat Biotechnol. 2007 Aug;25(8):903-10. doi: 10.1038/nbt1326. Epub 2007 Jul 29. Nat Biotechnol. 2007. PMID: 17664939 Free PMC article.
Ploidy reductions in murine fusion-derived hepatocytes.
Duncan AW, Hickey RD, Paulk NK, Culberson AJ, Olson SB, Finegold MJ, Grompe M. Duncan AW, et al. Among authors: paulk nk. PLoS Genet. 2009 Feb;5(2):e1000385. doi: 10.1371/journal.pgen.1000385. Epub 2009 Feb 20. PLoS Genet. 2009. PMID: 19229314 Free PMC article.
Ochronosis in a murine model of alkaptonuria is synonymous to that in the human condition.
Taylor AM, Preston AJ, Paulk NK, Sutherland H, Keenan CM, Wilson PJ, Wlodarski B, Grompe M, Ranganath LR, Gallagher JA, Jarvis JC. Taylor AM, et al. Among authors: paulk nk. Osteoarthritis Cartilage. 2012 Aug;20(8):880-6. doi: 10.1016/j.joca.2012.04.013. Epub 2012 Apr 24. Osteoarthritis Cartilage. 2012. PMID: 22542924 Free PMC article.
Rescue of Pompe disease in mice by AAV-mediated liver delivery of secretable acid α-glucosidase.
Puzzo F, Colella P, Biferi MG, Bali D, Paulk NK, Vidal P, Collaud F, Simon-Sola M, Charles S, Hardet R, Leborgne C, Meliani A, Cohen-Tannoudji M, Astord S, Gjata B, Sellier P, van Wittenberghe L, Vignaud A, Boisgerault F, Barkats M, Laforet P, Kay MA, Koeberl DD, Ronzitti G, Mingozzi F. Puzzo F, et al. Among authors: paulk nk. Sci Transl Med. 2017 Nov 29;9(418):eaam6375. doi: 10.1126/scitranslmed.aam6375. Sci Transl Med. 2017. PMID: 29187643 Free PMC article.
17 results