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149 results

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A microbiota-modulated checkpoint directs immunosuppressive intestinal T cells into cancers.
Fidelle M, Rauber C, Alves Costa Silva C, Tian AL, Lahmar I, de La Varende AM, Zhao L, Thelemaque C, Lebhar I, Messaoudene M, Pizzato E, Birebent R, Mbogning Fonkou MD, Zoppi S, Reni A, Dalban C, Leduc M, Ferrere G, Durand S, Ly P, Silvin A, Mulder K, Dutertre CA, Ginhoux F, Yonekura S, Roberti MP, Tidjani-Alou M, Terrisse S, Chen J, Kepp O, Schippers A, Wagner N, Suárez-Gosálvez J, Kobold S, Fahrner JE, Richard C, Bosq J, Lordello L, Vitali G, Galleron N, Quinquis B, Le Chatelier E, Blanchard L, Girard JP, Jarry A, Gervois N, Godefroy E, Labarrière N, Koschny R, Daillère R, Besse B, Truntzer C, Ghiringhelli F, Coatnoan N, Mhanna V, Klatzmann D, Drubay D, Albiges L, Thomas AM, Segata N, Danlos FX, Marabelle A, Routy B, Derosa L, Kroemer G, Zitvogel L. Fidelle M, et al. Among authors: kobold s. Science. 2023 Jun 9;380(6649):eabo2296. doi: 10.1126/science.abo2296. Epub 2023 Jun 9. Science. 2023. PMID: 37289890
Rational design of PD-1-CD28 immunostimulatory fusion proteins for CAR T cell therapy.
Lorenzini T, Cadilha BL, Obeck H, Benmebarek MR, Märkl F, Michaelides S, Strzalkowski T, Briukhovetska D, Müller PJ, Nandi S, Winter P, Majed L, Grünmeier R, Seifert M, Rausch S, Feuchtinger T, Endres S, Kobold S. Lorenzini T, et al. Among authors: kobold s. Br J Cancer. 2023 Sep;129(4):696-705. doi: 10.1038/s41416-023-02332-9. Epub 2023 Jul 4. Br J Cancer. 2023. PMID: 37400680 Free PMC article.
In vivo dynamics and anti-tumor effects of EpCAM-directed CAR T-cells against brain metastases from lung cancer.
Xu T, Karschnia P, Cadilha BL, Dede S, Lorenz M, Seewaldt N, Nikolaishvili E, Müller K, Blobner J, Teske N, Herold JJ, Rejeski K, Langer S, Obeck H, Lorenzini T, Mulazzani M, Zhang W, Ishikawa-Ankerhold H, Buchholz VR, Subklewe M, Thon N, Straube A, Tonn JC, Kobold S, von Baumgarten L. Xu T, et al. Among authors: kobold s. Oncoimmunology. 2023 Jan 13;12(1):2163781. doi: 10.1080/2162402X.2022.2163781. eCollection 2023. Oncoimmunology. 2023. PMID: 36687005 Free PMC article.
Programmable multispecific DNA-origami-based T-cell engagers.
Wagenbauer KF, Pham N, Gottschlich A, Kick B, Kozina V, Frank C, Trninic D, Stömmer P, Grünmeier R, Carlini E, Tsiverioti CA, Kobold S, Funke JJ, Dietz H. Wagenbauer KF, et al. Among authors: kobold s. Nat Nanotechnol. 2023 Nov;18(11):1319-1326. doi: 10.1038/s41565-023-01471-7. Epub 2023 Aug 17. Nat Nanotechnol. 2023. PMID: 37591933 Free PMC article.
Mitochondrial dysfunction promotes the transition of precursor to terminally exhausted T cells through HIF-1α-mediated glycolytic reprogramming.
Wu H, Zhao X, Hochrein SM, Eckstein M, Gubert GF, Knöpper K, Mansilla AM, Öner A, Doucet-Ladevèze R, Schmitz W, Ghesquière B, Theurich S, Dudek J, Gasteiger G, Zernecke A, Kobold S, Kastenmüller W, Vaeth M. Wu H, et al. Among authors: kobold s. Nat Commun. 2023 Oct 27;14(1):6858. doi: 10.1038/s41467-023-42634-3. Nat Commun. 2023. PMID: 37891230 Free PMC article.
9th Immunotherapy of Cancer conference (ITOC): A meeting report.
Dalloul I, Strzalkowski TJC, von Bergwelt-Baildon M, Nüssler V, Zielinski C, Kobold S. Dalloul I, et al. Among authors: kobold s. Hum Vaccin Immunother. 2022 Dec 30;18(7):2159706. doi: 10.1080/21645515.2022.2159706. Epub 2022 Dec 28. Hum Vaccin Immunother. 2022. PMID: 36576266 Free PMC article.
Migratory Engineering of T Cells for Cancer Therapy.
Michaelides S, Obeck H, Kechur D, Endres S, Kobold S. Michaelides S, et al. Among authors: kobold s. Vaccines (Basel). 2022 Oct 31;10(11):1845. doi: 10.3390/vaccines10111845. Vaccines (Basel). 2022. PMID: 36366354 Free PMC article. Review.
149 results