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Niche-based screening identifies small-molecule inhibitors of leukemia stem cells.
Hartwell KA, Miller PG, Mukherjee S, Kahn AR, Stewart AL, Logan DJ, Negri JM, Duvet M, Järås M, Puram R, Dancik V, Al-Shahrour F, Kindler T, Tothova Z, Chattopadhyay S, Hasaka T, Narayan R, Dai M, Huang C, Shterental S, Chu LP, Haydu JE, Shieh JH, Steensma DP, Munoz B, Bittker JA, Shamji AF, Clemons PA, Tolliday NJ, Carpenter AE, Gilliland DG, Stern AM, Moore MAS, Scadden DT, Schreiber SL, Ebert BL, Golub TR. Hartwell KA, et al. Among authors: negri jm. Nat Chem Biol. 2013 Dec;9(12):840-848. doi: 10.1038/nchembio.1367. Epub 2013 Oct 27. Nat Chem Biol. 2013. PMID: 24161946 Free PMC article.
Modulators of hepatic lipoprotein metabolism identified in a search for small-molecule inducers of tribbles pseudokinase 1 expression.
Nagiec MM, Skepner AP, Negri J, Eichhorn M, Kuperwasser N, Comer E, Muncipinto G, Subramanian A, Clish C, Musunuru K, Duvall JR, Foley M, Perez JR, Palmer MA. Nagiec MM, et al. Among authors: negri j. PLoS One. 2015 Mar 26;10(3):e0120295. doi: 10.1371/journal.pone.0120295. eCollection 2015. PLoS One. 2015. PMID: 25811180 Free PMC article.
Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI)-Mediated Lipid Transport.
Dockendorff C, Faloon PW, Yu M, Youngsaye W, Penman M, Nieland TJ, Nag PP, Lewis TA, Pu J, Bennion M, Negri J, Paterson C, Lam G, Dandapani S, Perez JR, Munoz B, Palmer MA, Schreiber SL, Krieger M. Dockendorff C, et al. Among authors: negri j. ACS Med Chem Lett. 2015 Feb 2;6(4):375-380. doi: 10.1021/ml500154q. eCollection 2015 Apr 9. ACS Med Chem Lett. 2015. PMID: 26478787 Free PMC article.
Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability.
Muratore CR, Zhou C, Liao M, Fernandez MA, Taylor WM, Lagomarsino VN, Pearse RV 2nd, Rice HC, Negri JM, He A, Srikanth P, Callahan DG, Shin T, Zhou M, Bennett DA, Noggle S, Love JC, Selkoe DJ, Young-Pearse TL. Muratore CR, et al. Among authors: negri jm. Stem Cell Reports. 2017 Dec 12;9(6):1868-1884. doi: 10.1016/j.stemcr.2017.10.015. Epub 2017 Nov 16. Stem Cell Reports. 2017. PMID: 29153990 Free PMC article.
Novel tricyclic glycal-based TRIB1 inducers that reprogram LDL metabolism in hepatic cells.
Nagiec MM, Duvall JR, Skepner AP, Howe EA, Bastien J, Comer E, Marie JC, Johnston SE, Negri J, Eichhorn M, Vantourout J, Clish C, Musunuru K, Foley M, Perez JR, Palmer MAJ. Nagiec MM, et al. Among authors: negri j. Medchemcomm. 2018 Sep 14;9(11):1831-1842. doi: 10.1039/c8md00297e. eCollection 2018 Nov 1. Medchemcomm. 2018. PMID: 30542533 Free PMC article.
107 results