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Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline.
Talbot K, Wang HY, Kazi H, Han LY, Bakshi KP, Stucky A, Fuino RL, Kawaguchi KR, Samoyedny AJ, Wilson RS, Arvanitakis Z, Schneider JA, Wolf BA, Bennett DA, Trojanowski JQ, Arnold SE. Talbot K, et al. Among authors: wang hy. J Clin Invest. 2012 Apr;122(4):1316-38. doi: 10.1172/JCI59903. J Clin Invest. 2012. PMID: 22476197 Free PMC article.
Brain Insulin Signaling, Alzheimer Disease Pathology, and Cognitive Function.
Arvanitakis Z, Wang HY, Capuano AW, Khan A, Taïb B, Anokye-Danso F, Schneider JA, Bennett DA, Ahima RS, Arnold SE. Arvanitakis Z, et al. Among authors: wang hy. Ann Neurol. 2020 Sep;88(3):513-525. doi: 10.1002/ana.25826. Epub 2020 Jul 27. Ann Neurol. 2020. PMID: 32557841 Free PMC article.
Brain insulin signaling and cerebrovascular disease in human postmortem brain.
Arvanitakis Z, Capuano AW, Wang HY, Schneider JA, Kapasi A, Bennett DA, Ahima RS, Arnold SE. Arvanitakis Z, et al. Among authors: wang hy. Acta Neuropathol Commun. 2021 Apr 15;9(1):71. doi: 10.1186/s40478-021-01176-9. Acta Neuropathol Commun. 2021. PMID: 33858515 Free PMC article.
Brain insulin resistance in type 2 diabetes and Alzheimer disease: concepts and conundrums.
Arnold SE, Arvanitakis Z, Macauley-Rambach SL, Koenig AM, Wang HY, Ahima RS, Craft S, Gandy S, Buettner C, Stoeckel LE, Holtzman DM, Nathan DM. Arnold SE, et al. Among authors: wang hy. Nat Rev Neurol. 2018 Mar;14(3):168-181. doi: 10.1038/nrneurol.2017.185. Epub 2018 Jan 29. Nat Rev Neurol. 2018. PMID: 29377010 Free PMC article. Review.
[No title available]
[No authors listed] [No authors listed] PMID: 35109097
Prenatal Cocaine Exposure Upregulates BDNF-TrkB Signaling.
Stucky A, Bakshi KP, Friedman E, Wang HY. Stucky A, et al. Among authors: wang hy. PLoS One. 2016 Aug 5;11(8):e0160585. doi: 10.1371/journal.pone.0160585. eCollection 2016. PLoS One. 2016. PMID: 27494324 Free PMC article. Retracted.
5,092 results