Brekken RA - Search Results

1

Dichotomous effects of VEGF-A on adipose tissue dysfunction.

Sun K, Wernstedt Asterholm I, Kusminski CM, Bueno AC, Wang ZV, Pollard JW, Brekken RA, Scherer PE. Sun K, et al. Among authors: brekken ra. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5874-9. doi: 10.1073/pnas.1200447109. Epub 2012 Mar 26. Proc Natl Acad Sci U S A. 2012. PMID: 22451920 Free PMC article.

2

A peptoid antagonist of VEGF receptor 2 recognizes a 'hotspot' in the extracellular domain distinct from the hormone-binding site.

Udugamasooriya DG, Ritchie C, Brekken RA, Kodadek T. Udugamasooriya DG, et al. Among authors: brekken ra. Bioorg Med Chem. 2008 Jun 15;16(12):6338-43. doi: 10.1016/j.bmc.2008.05.015. Epub 2008 May 9. Bioorg Med Chem. 2008. PMID: 18501615 Free PMC article.

3

The Adnectin CT-322 is a novel VEGF receptor 2 inhibitor that decreases tumor burden in an orthotopic mouse model of pancreatic cancer.

Dineen SP, Sullivan LA, Beck AW, Miller AF, Carbon JG, Mamluk R, Wong H, Brekken RA. Dineen SP, et al. Among authors: brekken ra. BMC Cancer. 2008 Nov 27;8:352. doi: 10.1186/1471-2407-8-352. BMC Cancer. 2008. PMID: 19038046 Free PMC article.

4

Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue.

Halberg N, Khan T, Trujillo ME, Wernstedt-Asterholm I, Attie AD, Sherwani S, Wang ZV, Landskroner-Eiger S, Dineen S, Magalang UJ, Brekken RA, Scherer PE. Halberg N, et al. Among authors: brekken ra. Mol Cell Biol. 2009 Aug;29(16):4467-83. doi: 10.1128/MCB.00192-09. Epub 2009 Jun 22. Mol Cell Biol. 2009. PMID: 19546236 Free PMC article.

5

Rgs16 and Rgs8 in embryonic endocrine pancreas and mouse models of diabetes.

Villasenor A, Wang ZV, Rivera LB, Ocal O, Asterholm IW, Scherer PE, Brekken RA, Cleaver O, Wilkie TM. Villasenor A, et al. Among authors: brekken ra. Dis Model Mech. 2010 Sep-Oct;3(9-10):567-80. doi: 10.1242/dmm.003210. Epub 2010 Jul 8. Dis Model Mech. 2010. PMID: 20616094 Free PMC article.

6

Lack of "immunological fitness" during fasting in metabolically challenged animals.

Asterholm IW, McDonald J, Blanchard PG, Sinha M, Xiao Q, Mistry J, Rutkowski JM, Deshaies Y, Brekken RA, Scherer PE. Asterholm IW, et al. Among authors: brekken ra. J Lipid Res. 2012 Jul;53(7):1254-67. doi: 10.1194/jlr.M021725. Epub 2012 Apr 13. J Lipid Res. 2012. PMID: 22504909 Free PMC article.

7

Actions of the protein kinase WNK1 on endothelial cells are differentially mediated by its substrate kinases OSR1 and SPAK.

Dbouk HA, Weil LM, Perera GK, Dellinger MT, Pearson G, Brekken RA, Cobb MH. Dbouk HA, et al. Among authors: brekken ra. Proc Natl Acad Sci U S A. 2014 Nov 11;111(45):15999-6004. doi: 10.1073/pnas.1419057111. Epub 2014 Oct 31. Proc Natl Acad Sci U S A. 2014. PMID: 25362046 Free PMC article.

8

Loss of Tbk1 kinase activity protects mice from diet-induced metabolic dysfunction.

Cruz VH, Arner EN, Wynne KW, Scherer PE, Brekken RA. Cruz VH, et al. Among authors: brekken ra. Mol Metab. 2018 Oct;16:139-149. doi: 10.1016/j.molmet.2018.06.007. Epub 2018 Jun 11. Mol Metab. 2018. PMID: 29935921 Free PMC article.

9

β1 Syntrophin Supports Autophagy Initiation and Protects against Cerulein-Induced Acute Pancreatitis.

Ye R, Onodera T, Blanchard PG, Kusminski CM, Esser V, Brekken RA, Scherer PE. Ye R, et al. Among authors: brekken ra. Am J Pathol. 2019 Apr;189(4):813-825. doi: 10.1016/j.ajpath.2019.01.002. Epub 2019 Jan 14. Am J Pathol. 2019. PMID: 30653956 Free PMC article.

10

Selective blockade of vascular endothelial growth factor receptor 2 with an antibody against tumor-derived vascular endothelial growth factor controls the growth of human pancreatic adenocarcinoma xenografts.

Holloway SE, Beck AW, Shivakumar L, Shih J, Fleming JB, Brekken RA. Holloway SE, et al. Among authors: brekken ra. Ann Surg Oncol. 2006 Aug;13(8):1145-55. doi: 10.1245/ASO.2006.05.049. Epub 2006 Jun 21. Ann Surg Oncol. 2006. PMID: 16791450

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