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Treatment-emergent mutations in NAEβ confer resistance to the NEDD8-activating enzyme inhibitor MLN4924.
Cancer Cell. 2012 Mar 20;21(3):388-401. doi: 10.1016/j.ccr.2012.02.009.
Cancer Cell. 2012.
PMID: 22439935
Free article.
Mechanistic studies on activation of ubiquitin and di-ubiquitin-like protein, FAT10, by ubiquitin-like modifier activating enzyme 6, Uba6.
Gavin JM, Chen JJ, Liao H, Rollins N, Yang X, Xu Q, Ma J, Loke HK, Lingaraj T, Brownell JE, Mallender WD, Gould AE, Amidon BS, Dick LR.
Gavin JM, et al. Among authors: amidon bs.
J Biol Chem. 2012 May 4;287(19):15512-22. doi: 10.1074/jbc.M111.336198. Epub 2012 Mar 15.
J Biol Chem. 2012.
PMID: 22427669
Free PMC article.
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A small-molecule inhibitor of the ubiquitin activating enzyme for cancer treatment.
Hyer ML, Milhollen MA, Ciavarri J, Fleming P, Traore T, Sappal D, Huck J, Shi J, Gavin J, Brownell J, Yang Y, Stringer B, Griffin R, Bruzzese F, Soucy T, Duffy J, Rabino C, Riceberg J, Hoar K, Lublinsky A, Menon S, Sintchak M, Bump N, Pulukuri SM, Langston S, Tirrell S, Kuranda M, Veiby P, Newcomb J, Li P, Wu JT, Powe J, Dick LR, Greenspan P, Galvin K, Manfredi M, Claiborne C, Amidon BS, Bence NF.
Hyer ML, et al. Among authors: amidon bs.
Nat Med. 2018 Feb;24(2):186-193. doi: 10.1038/nm.4474. Epub 2018 Jan 15.
Nat Med. 2018.
PMID: 29334375
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Inhibition of NEDD8-activating enzyme induces rereplication and apoptosis in human tumor cells consistent with deregulating CDT1 turnover.
Milhollen MA, Narayanan U, Soucy TA, Veiby PO, Smith PG, Amidon B.
Milhollen MA, et al.
Cancer Res. 2011 Apr 15;71(8):3042-51. doi: 10.1158/0008-5472.CAN-10-2122. Epub 2011 Apr 12.
Cancer Res. 2011.
PMID: 21487042
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MLN0905, a small-molecule plk1 inhibitor, induces antitumor responses in human models of diffuse large B-cell lymphoma.
Shi JQ, Lasky K, Shinde V, Stringer B, Qian MG, Liao D, Liu R, Driscoll D, Nestor MT, Amidon BS, Rao Y, Duffey MO, Manfredi MG, Vos TJ, D' Amore N, Hyer ML.
Shi JQ, et al. Among authors: amidon bs.
Mol Cancer Ther. 2012 Sep;11(9):2045-53. doi: 10.1158/1535-7163.MCT-11-1036. Epub 2012 May 18.
Mol Cancer Ther. 2012.
PMID: 22609854
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KRAS Genotype Correlates with Proteasome Inhibitor Ixazomib Activity in Preclinical In Vivo Models of Colon and Non-Small Cell Lung Cancer: Potential Role of Tumor Metabolism.
Chattopadhyay N, Berger AJ, Koenig E, Bannerman B, Garnsey J, Bernard H, Hales P, Maldonado Lopez A, Yang Y, Donelan J, Jordan K, Tirrell S, Stringer B, Xia C, Hather G, Galvin K, Manfredi M, Rhodes N, Amidon B.
Chattopadhyay N, et al.
PLoS One. 2015 Dec 28;10(12):e0144825. doi: 10.1371/journal.pone.0144825. eCollection 2015.
PLoS One. 2015.
PMID: 26709701
Free PMC article.
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Plk1 inhibition causes post-mitotic DNA damage and senescence in a range of human tumor cell lines.
Driscoll DL, Chakravarty A, Bowman D, Shinde V, Lasky K, Shi J, Vos T, Stringer B, Amidon B, D'Amore N, Hyer ML.
Driscoll DL, et al.
PLoS One. 2014 Nov 3;9(11):e111060. doi: 10.1371/journal.pone.0111060. eCollection 2014.
PLoS One. 2014.
PMID: 25365521
Free PMC article.
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Microarray approach for cloned library quality assessment and the comprehensive identification of positives from library screens.
Blackman RK, Amidon BS.
Blackman RK, et al. Among authors: amidon bs.
Biotechniques. 2004 Oct;37(4):536, 538, 540. doi: 10.2144/04374BM02.
Biotechniques. 2004.
PMID: 15517962
Free article.
No abstract available.
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