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Structural approaches to probing metal interaction with proteins.
Parker LJ, Ascher DB, Gao C, Miles LA, Harris HH, Parker MW. Parker LJ, et al. Among authors: harris hh. J Inorg Biochem. 2012 Oct;115:138-47. doi: 10.1016/j.jinorgbio.2012.02.015. Epub 2012 Mar 3. J Inorg Biochem. 2012. PMID: 22437159 Review.
Studies of glutathione transferase P1-1 bound to a platinum(IV)-based anticancer compound reveal the molecular basis of its activation.
Parker LJ, Italiano LC, Morton CJ, Hancock NC, Ascher DB, Aitken JB, Harris HH, Campomanes P, Rothlisberger U, De Luca A, Lo Bello M, Ang WH, Dyson PJ, Parker MW. Parker LJ, et al. Among authors: harris hh. Chemistry. 2011 Jul 4;17(28):7806-16. doi: 10.1002/chem.201100586. Epub 2011 Jun 16. Chemistry. 2011. PMID: 21681839
Glutathione transferase P1-1 as an arsenic drug-sequestering enzyme.
Parker LJ, Bocedi A, Ascher DB, Aitken JB, Harris HH, Lo Bello M, Ricci G, Morton CJ, Parker MW. Parker LJ, et al. Among authors: harris hh. Protein Sci. 2017 Feb;26(2):317-326. doi: 10.1002/pro.3084. Epub 2016 Dec 14. Protein Sci. 2017. PMID: 27863446 Free PMC article.
A Multimodal Spectroscopic Imaging Method To Characterize the Metal and Macromolecular Content of Proteinaceous Aggregates ("Amyloid Plaques").
Summers KL, Fimognari N, Hollings A, Kiernan M, Lam V, Tidy RJ, Paterson D, Tobin MJ, Takechi R, George GN, Pickering IJ, Mamo JC, Harris HH, Hackett MJ. Summers KL, et al. Among authors: harris hh. Biochemistry. 2017 Aug 15;56(32):4107-4116. doi: 10.1021/acs.biochem.7b00262. Epub 2017 Jul 18. Biochemistry. 2017. PMID: 28718623
A two-step valence tautomeric transition in a dinuclear cobalt complex.
Alley KG, Poneti G, Aitken JB, Hocking RK, Moubaraki B, Murray KS, Abrahams BF, Harris HH, Sorace L, Boskovic C. Alley KG, et al. Among authors: harris hh. Inorg Chem. 2012 Apr 2;51(7):3944-6. doi: 10.1021/ic3002527. Epub 2012 Mar 20. Inorg Chem. 2012. PMID: 22432512
156 results