Ascher DB - Search Results

1

Structural approaches to probing metal interaction with proteins.

Parker LJ, Ascher DB, Gao C, Miles LA, Harris HH, Parker MW. Parker LJ, et al. Among authors: ascher db. J Inorg Biochem. 2012 Oct;115:138-47. doi: 10.1016/j.jinorgbio.2012.02.015. Epub 2012 Mar 3. J Inorg Biochem. 2012. PMID: 22437159 Review.

2

Crystallization and preliminary X-ray diffraction analysis of the Fab fragment of WO2, an antibody specific for the Abeta peptides associated with Alzheimer's disease.

Wun KS, Miles LA, Crespi GA, Wycherley K, Ascher DB, Barnham KJ, Cappai R, Beyreuther K, Masters CL, Parker MW, McKinstry WJ. Wun KS, et al. Among authors: ascher db. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008 May 1;64(Pt 5):438-41. doi: 10.1107/S1744309108011718. Epub 2008 Apr 30. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2008. PMID: 18453721 Free PMC article.

3

Identification of modulating residues defining the catalytic cleft of insulin-regulated aminopeptidase.

Ye S, Chai SY, Lew RA, Ascher DB, Morton CJ, Parker MW, Albiston AL. Ye S, et al. Among authors: ascher db. Biochem Cell Biol. 2008 Jun;86(3):251-61. doi: 10.1139/o08-037. Biochem Cell Biol. 2008. PMID: 18523486

4

Identification and characterization of a new cognitive enhancer based on inhibition of insulin-regulated aminopeptidase.

Albiston AL, Morton CJ, Ng HL, Pham V, Yeatman HR, Ye S, Fernando RN, De Bundel D, Ascher DB, Mendelsohn FA, Parker MW, Chai SY. Albiston AL, et al. Among authors: ascher db. FASEB J. 2008 Dec;22(12):4209-17. doi: 10.1096/fj.08-112227. Epub 2008 Aug 20. FASEB J. 2008. PMID: 18716029

5

Development of cognitive enhancers based on inhibition of insulin-regulated aminopeptidase.

Chai SY, Yeatman HR, Parker MW, Ascher DB, Thompson PE, Mulvey HT, Albiston AL. Chai SY, et al. Among authors: ascher db. BMC Neurosci. 2008 Dec 3;9 Suppl 2(Suppl 2):S14. doi: 10.1186/1471-2202-9-S2-S14. BMC Neurosci. 2008. PMID: 19090987 Free PMC article. Review.

6

Regulation of insulin-regulated membrane aminopeptidase activity by its C-terminal domain.

Ascher DB, Cromer BA, Morton CJ, Volitakis I, Cherny RA, Albiston AL, Chai SY, Parker MW. Ascher DB, et al. Biochemistry. 2011 Apr 5;50(13):2611-22. doi: 10.1021/bi101893w. Epub 2011 Mar 9. Biochemistry. 2011. PMID: 21348480

7

Studies of glutathione transferase P1-1 bound to a platinum(IV)-based anticancer compound reveal the molecular basis of its activation.

Parker LJ, Italiano LC, Morton CJ, Hancock NC, Ascher DB, Aitken JB, Harris HH, Campomanes P, Rothlisberger U, De Luca A, Lo Bello M, Ang WH, Dyson PJ, Parker MW. Parker LJ, et al. Among authors: ascher db. Chemistry. 2011 Jul 4;17(28):7806-16. doi: 10.1002/chem.201100586. Epub 2011 Jun 16. Chemistry. 2011. PMID: 21681839

8

Crystallization and preliminary X-ray diffraction analysis of human endoplasmic reticulum aminopeptidase 2.

Ascher DB, Polekhina G, Parker MW. Ascher DB, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Apr 1;68(Pt 4):468-71. doi: 10.1107/S1744309112006963. Epub 2012 Mar 28. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012. PMID: 22505422 Free PMC article.

9

Structural studies of Streptococcus pyogenes streptolysin O provide insights into the early steps of membrane penetration.

Feil SC, Ascher DB, Kuiper MJ, Tweten RK, Parker MW. Feil SC, et al. Among authors: ascher db. J Mol Biol. 2014 Feb 20;426(4):785-92. doi: 10.1016/j.jmb.2013.11.020. Epub 2013 Dec 3. J Mol Biol. 2014. PMID: 24316049 Free PMC article.

10

Crystallization and preliminary X-ray diffraction analysis of the Fab portion of the Alzheimer's disease immunotherapy candidate bapineuzumab complexed with amyloid-β.

Crespi GA, Ascher DB, Parker MW, Miles LA. Crespi GA, et al. Among authors: ascher db. Acta Crystallogr F Struct Biol Commun. 2014 Mar;70(Pt 3):374-7. doi: 10.1107/S2053230X14001642. Epub 2014 Feb 20. Acta Crystallogr F Struct Biol Commun. 2014. PMID: 24598931 Free PMC article.

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