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Cancer and the bromodomains of BAF180.
Biochem Soc Trans. 2012 Apr;40(2):364-9. doi: 10.1042/BST20110754.
Biochem Soc Trans. 2012.
PMID: 22435813
Review.
BAF180 promotes cohesion and prevents genome instability and aneuploidy.
Brownlee PM, Chambers AL, Cloney R, Bianchi A, Downs JA.
Brownlee PM, et al.
Cell Rep. 2014 Mar 27;6(6):973-981. doi: 10.1016/j.celrep.2014.02.012. Epub 2014 Mar 6.
Cell Rep. 2014.
PMID: 24613357
Free PMC article.
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The SWI/SNF chromatin remodelling complex: Its role in maintaining genome stability and preventing tumourigenesis.
Brownlee PM, Meisenberg C, Downs JA.
Brownlee PM, et al.
DNA Repair (Amst). 2015 Aug;32:127-133. doi: 10.1016/j.dnarep.2015.04.023. Epub 2015 May 1.
DNA Repair (Amst). 2015.
PMID: 25981841
Review.
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Discovery and Optimization of a Selective Ligand for the Switch/Sucrose Nonfermenting-Related Bromodomains of Polybromo Protein-1 by the Use of Virtual Screening and Hydration Analysis.
Myrianthopoulos V, Gaboriaud-Kolar N, Tallant C, Hall ML, Grigoriou S, Brownlee PM, Fedorov O, Rogers C, Heidenreich D, Wanior M, Drosos N, Mexia N, Savitsky P, Bagratuni T, Kastritis E, Terpos E, Filippakopoulos P, Müller S, Skaltsounis AL, Downs JA, Knapp S, Mikros E.
Myrianthopoulos V, et al. Among authors: brownlee pm.
J Med Chem. 2016 Oct 13;59(19):8787-8803. doi: 10.1021/acs.jmedchem.6b00355. Epub 2016 Sep 27.
J Med Chem. 2016.
PMID: 27617704
Free PMC article.
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The two different isoforms of the RSC chromatin remodeling complex play distinct roles in DNA damage responses.
Chambers AL, Brownlee PM, Durley SC, Beacham T, Kent NA, Downs JA.
Chambers AL, et al. Among authors: brownlee pm.
PLoS One. 2012;7(2):e32016. doi: 10.1371/journal.pone.0032016. Epub 2012 Feb 16.
PLoS One. 2012.
PMID: 22359657
Free PMC article.
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High replication stress and limited Rad51-mediated DNA repair capacity, but not oxidative stress, underlie oligodendrocyte precursor cell radiosensitivity.
Berger ND, Brownlee PM, Chen MJ, Morrison H, Osz K, Ploquin NP, Chan JA, Goodarzi AA.
Berger ND, et al. Among authors: brownlee pm.
NAR Cancer. 2022 Apr 12;4(2):zcac012. doi: 10.1093/narcan/zcac012. eCollection 2022 Jun.
NAR Cancer. 2022.
PMID: 35425901
Free PMC article.
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Unsprung traps keep PARP inhibitors effective.
Brownlee PM, Provencher L, Goodarzi AA.
Brownlee PM, et al.
Nat Cell Biol. 2022 Jan;24(1):2-4. doi: 10.1038/s41556-021-00819-2.
Nat Cell Biol. 2022.
PMID: 35013555
No abstract available.
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