Xu H - Search Results

1

Indole-propionic acid derivatives as potent, S1P3-sparing and EAE efficacious sphingosine-1-phosphate 1 (S1P1) receptor agonists.

Meng Q, Zhao B, Xu Q, Xu X, Deng G, Li C, Luan L, Ren F, Wang H, Xu H, Xu Y, Zhang H, Xiang JN, Elliott JD, Guo TB, Zhao Y, Zhang W, Lu H, Lin X. Meng Q, et al. Among authors: xu q, xu x, xu h, xu y. Bioorg Med Chem Lett. 2012 Apr 15;22(8):2794-7. doi: 10.1016/j.bmcl.2012.02.083. Epub 2012 Mar 3. Bioorg Med Chem Lett. 2012. PMID: 22429468

2

Discovery of thiadiazole amides as potent, S1P₃-sparing agonists of sphingosine-1-phosphate 1 (S1P₁) receptor.

Xu H, Zhang H, Luan L, Xu Y, Li C, Wang Y, Han F, Yang T, Ren F, Xiang JN, Elliott JD, Zhao Y, Guo TB, Lu H, Zhang W, Hirst D, Lindon M, Lin X. Xu H, et al. Among authors: xu y. Bioorg Med Chem Lett. 2012 Apr 1;22(7):2456-9. doi: 10.1016/j.bmcl.2012.02.016. Epub 2012 Feb 15. Bioorg Med Chem Lett. 2012. PMID: 22386243

3

Discovery of novel 1,2,4-thiadiazole derivatives as potent, orally active agonists of sphingosine 1-phosphate receptor subtype 1 (S1P(1)).

Ren F, Deng G, Wang H, Luan L, Meng Q, Xu Q, Xu H, Xu X, Zhang H, Zhao B, Li C, Guo TB, Yang J, Zhang W, Zhao Y, Jia Q, Lu H, Xiang JN, Elliott JD, Lin X. Ren F, et al. Among authors: xu q, xu h, xu x. J Med Chem. 2012 May 10;55(9):4286-96. doi: 10.1021/jm2016107. Epub 2012 Apr 20. J Med Chem. 2012. PMID: 22500954

4

Discovery of CNS Penetrant CXCR2 Antagonists for the Potential Treatment of CNS Demyelinating Disorders.

Xu H, Lu H, Xu Z, Luan L, Li C, Xu Y, Dong K, Zhang J, Li X, Li Y, Liu G, Gong S, Zhao YG, Liu A, Zhang Y, Zhang W, Cai X, Xiang JN, Elliott JD, Lin X. Xu H, et al. Among authors: xu y, xu z. ACS Med Chem Lett. 2016 Feb 8;7(4):397-402. doi: 10.1021/acsmedchemlett.5b00489. eCollection 2016 Apr 14. ACS Med Chem Lett. 2016. PMID: 27096048 Free PMC article.

5

Discovery of new thienopyrimidine derivatives as potent and orally efficacious phosphoinositide 3-kinase inhibitors.

Lin S, Wang C, Ji M, Wu D, Lv Y, Sheng L, Han F, Dong Y, Zhang K, Yang Y, Li Y, Chen X, Xu H. Lin S, et al. Among authors: xu h. Bioorg Med Chem. 2018 Feb 1;26(3):637-646. doi: 10.1016/j.bmc.2017.12.025. Epub 2017 Dec 23. Bioorg Med Chem. 2018. PMID: 29305298

6

Design, Synthesis, and Biological Evaluation of Novel Pyrimido[4,5-b]indole Derivatives Against Gram-Negative Multidrug-Resistant Pathogens.

Kong Q, Pan W, Xu H, Xue Y, Guo B, Meng X, Luo C, Wang T, Zhang S, Yang Y. Kong Q, et al. Among authors: xu h. J Med Chem. 2021 Jun 24;64(12):8644-8665. doi: 10.1021/acs.jmedchem.1c00621. Epub 2021 Jun 3. J Med Chem. 2021. PMID: 34080858

7

Identification of novel 7-amino-5-methyl-1,6-naphthyridin-2(1H)-one derivatives as potent PI3K/mTOR dual inhibitors.

Lin S, Han F, Liu P, Tao J, Zhong X, Liu X, Yi C, Xu H. Lin S, et al. Among authors: xu h. Bioorg Med Chem Lett. 2014 Feb 1;24(3):790-3. doi: 10.1016/j.bmcl.2013.12.112. Epub 2014 Jan 3. Bioorg Med Chem Lett. 2014. PMID: 24433860

8

Discovery of novel reversible monoacylglycerol lipase inhibitors via docking-based virtual screening.

Xiong F, Ding X, Zhang H, Luo X, Chen K, Jiang H, Luo C, Xu H. Xiong F, et al. Among authors: xu h. Bioorg Med Chem Lett. 2021 Jun 1;41:127986. doi: 10.1016/j.bmcl.2021.127986. Epub 2021 Mar 22. Bioorg Med Chem Lett. 2021. PMID: 33766770

9

Identification of novel anti-inflammatory Nur77 modulators by virtual screening.

Ding X, Zhao Z, Wu Y, Zhang H, Chen K, Luo C, Luo X, Xu H. Ding X, et al. Among authors: xu h. Bioorg Chem. 2021 Jul;112:104912. doi: 10.1016/j.bioorg.2021.104912. Epub 2021 Apr 20. Bioorg Chem. 2021. PMID: 33933804

10

Synthesis and structure-activity relationships of PI3K/mTOR dual inhibitors from a series of 2-amino-4-methylpyrido[2,3-d]pyrimidine derivatives.

Han F, Lin S, Liu P, Tao J, Yi C, Xu H. Han F, et al. Among authors: xu h. Bioorg Med Chem Lett. 2014 Sep 15;24(18):4538-4541. doi: 10.1016/j.bmcl.2014.07.073. Epub 2014 Aug 7. Bioorg Med Chem Lett. 2014. PMID: 25139570

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