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A biophysical analysis of the tetratricopeptide repeat-rich mitochondrial import receptor, Tom70, reveals an elongated monomer that is inherently flexible, unstable, and unfolds via a multistate pathway.
Beddoe T, Bushell SR, Perugini MA, Lithgow T, Mulhern TD, Bottomley SP, Rossjohn J. Beddoe T, et al. Among authors: perugini ma. J Biol Chem. 2004 Nov 5;279(45):46448-54. doi: 10.1074/jbc.M405639200. Epub 2004 Aug 16. J Biol Chem. 2004. PMID: 15316022 Free article.
Defining the interaction of perforin with calcium and the phospholipid membrane.
Traore DA, Brennan AJ, Law RH, Dogovski C, Perugini MA, Lukoyanova N, Leung EW, Norton RS, Lopez JA, Browne KA, Yagita H, Lloyd GJ, Ciccone A, Verschoor S, Trapani JA, Whisstock JC, Voskoboinik I. Traore DA, et al. Among authors: perugini ma. Biochem J. 2013 Dec 15;456(3):323-35. doi: 10.1042/BJ20130999. Biochem J. 2013. PMID: 24070258
The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4.
Moradi S, Berry R, Pymm P, Hitchen C, Beckham SA, Wilce MC, Walpole NG, Clements CS, Reid HH, Perugini MA, Brooks AG, Rossjohn J, Vivian JP. Moradi S, et al. Among authors: perugini ma. J Biol Chem. 2015 Apr 17;290(16):10460-71. doi: 10.1074/jbc.M114.612291. Epub 2015 Mar 10. J Biol Chem. 2015. PMID: 25759384 Free PMC article.
141 results