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The radioprotective 105/MD-1 complex contributes to diet-induced obesity and adipose tissue inflammation.
Watanabe Y, Nakamura T, Ishikawa S, Fujisaka S, Usui I, Tsuneyama K, Ichihara Y, Wada T, Hirata Y, Suganami T, Izaki H, Akira S, Miyake K, Kanayama HO, Shimabukuro M, Sata M, Sasaoka T, Ogawa Y, Tobe K, Takatsu K, Nagai Y. Watanabe Y, et al. Among authors: tobe k. Diabetes. 2012 May;61(5):1199-209. doi: 10.2337/db11-1182. Epub 2012 Mar 6. Diabetes. 2012. PMID: 22396206 Free PMC article.
Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia.
Kubota N, Tobe K, Terauchi Y, Eto K, Yamauchi T, Suzuki R, Tsubamoto Y, Komeda K, Nakano R, Miki H, Satoh S, Sekihara H, Sciacchitano S, Lesniak M, Aizawa S, Nagai R, Kimura S, Akanuma Y, Taylor SI, Kadowaki T. Kubota N, et al. Among authors: tobe k. Diabetes. 2000 Nov;49(11):1880-9. doi: 10.2337/diabetes.49.11.1880. Diabetes. 2000. PMID: 11078455
Subcellular localization of insulin receptor substrate family proteins associated with phosphatidylinositol 3-kinase activity and alterations in lipolysis in primary mouse adipocytes from IRS-1 null mice.
Tsuji Y, Kaburagi Y, Terauchi Y, Satoh S, Kubota N, Tamemoto H, Kraemer FB, Sekihara H, Aizawa S, Akanuma Y, Tobe K, Kimura S, Kadowaki T. Tsuji Y, et al. Among authors: tobe k. Diabetes. 2001 Jun;50(6):1455-63. doi: 10.2337/diabetes.50.6.1455. Diabetes. 2001. PMID: 11375348
Genetic variation in the gene encoding adiponectin is associated with an increased risk of type 2 diabetes in the Japanese population.
Hara K, Boutin P, Mori Y, Tobe K, Dina C, Yasuda K, Yamauchi T, Otabe S, Okada T, Eto K, Kadowaki H, Hagura R, Akanuma Y, Yazaki Y, Nagai R, Taniyama M, Matsubara K, Yoda M, Nakano Y, Tomita M, Kimura S, Ito C, Froguel P, Kadowaki T. Hara K, et al. Among authors: tobe k. Diabetes. 2002 Feb;51(2):536-40. doi: 10.2337/diabetes.51.2.536. Diabetes. 2002. PMID: 11812766
The role of PPARgamma in high-fat diet-induced obesity and insulin resistance.
Kadowaki T, Hara K, Kubota N, Tobe K, Terauchi Y, Yamauchi T, Eto K, Kadowaki H, Noda M, Hagura R, Akanuma Y. Kadowaki T, et al. Among authors: tobe k. J Diabetes Complications. 2002 Jan-Feb;16(1):41-5. doi: 10.1016/s1056-8727(01)00206-9. J Diabetes Complications. 2002. PMID: 11872365 Review.
Cloning, bacterial expression, and unique structure of adenosylhomocysteine hydrolase-like protein 1, or inositol 1,4,5-triphosphate receptor-binding protein from mouse kidney.
Gomi T, Takusagawa F, Nishizawa M, Agussalim B, Usui I, Sugiyama E, Taki H, Shinoda K, Hounoki H, Miwa T, Tobe K, Kobayashi M, Ishimoto T, Ogawa H, Mori H. Gomi T, et al. Among authors: tobe k. Biochim Biophys Acta. 2008 Nov;1784(11):1786-94. doi: 10.1016/j.bbapap.2008.08.016. Epub 2008 Sep 5. Biochim Biophys Acta. 2008. PMID: 18804558
Characterization of diabetic nephropathy in CaM kinase IIalpha (Thr286Asp) transgenic mice.
Suzuki H, Kato I, Usui I, Takasaki I, Tabuchi Y, Oya T, Tsuneyama K, Kawaguchi H, Hiraga K, Takasawa S, Okamoto H, Tobe K, Sasahara M. Suzuki H, et al. Among authors: tobe k. Biochem Biophys Res Commun. 2009 Jan 30;379(1):38-42. doi: 10.1016/j.bbrc.2008.11.143. Epub 2008 Dec 12. Biochem Biophys Res Commun. 2009. PMID: 19070598
455 results