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The radioprotective 105/MD-1 complex contributes to diet-induced obesity and adipose tissue inflammation.
Watanabe Y, Nakamura T, Ishikawa S, Fujisaka S, Usui I, Tsuneyama K, Ichihara Y, Wada T, Hirata Y, Suganami T, Izaki H, Akira S, Miyake K, Kanayama HO, Shimabukuro M, Sata M, Sasaoka T, Ogawa Y, Tobe K, Takatsu K, Nagai Y. Watanabe Y, et al. Among authors: sasaoka t. Diabetes. 2012 May;61(5):1199-209. doi: 10.2337/db11-1182. Epub 2012 Mar 6. Diabetes. 2012. PMID: 22396206 Free PMC article.
Involvement of heat shock protein 90 in the degradation of mutant insulin receptors by the proteasome.
Imamura T, Haruta T, Takata Y, Usui I, Iwata M, Ishihara H, Ishiki M, Ishibashi O, Ueno E, Sasaoka T, Kobayashi M. Imamura T, et al. Among authors: sasaoka t. J Biol Chem. 1998 May 1;273(18):11183-8. doi: 10.1074/jbc.273.18.11183. J Biol Chem. 1998. PMID: 9556607 Free article.
The extreme insulin resistance of these patients was found to be caused by the decreased number of insulin receptors on the cell surface, due to the intracellular rapid degradation (Imamura, T., Takata, Y., Sasaoka, T., Takada, Y., Morioka, H., Haruta, T
The extreme insulin resistance of these patients was found to be caused by the decreased number of insulin receptors on the cell surface, du …
356 results