Houpis IN - Search Results

1

Stereoselective C-glycosylation reactions with arylzinc reagents.

Lemaire S, Houpis IN, Xiao T, Li J, Digard E, Gozlan C, Liu R, Gavryushin A, Diène C, Wang Y, Farina V, Knochel P. Lemaire S, et al. Among authors: houpis in. Org Lett. 2012 Mar 16;14(6):1480-3. doi: 10.1021/ol300220p. Epub 2012 Mar 2. Org Lett. 2012. PMID: 22385274

2

Regioselective cross-coupling reactions of boronic acids with dihalo heterocycles.

Houpis IN, Liu R, Wu Y, Yuan Y, Wang Y, Nettekoven U. Houpis IN, et al. J Org Chem. 2010 Oct 15;75(20):6965-8. doi: 10.1021/jo101223z. J Org Chem. 2010. PMID: 20839822

3

Olefin Preparation via Palladium-Catalyzed Oxidative De-Azotative and De-Sulfitative Internal Cross-Coupling of Sulfonylhydrazones.

Tan H, Houpis I, Liu R, Wang Y, Chen Z. Tan H, et al. Org Lett. 2015 Jul 17;17(14):3548-51. doi: 10.1021/acs.orglett.5b01494. Epub 2015 Jul 8. Org Lett. 2015. PMID: 26154875

4

Practical synthesis of (2'R)-2'-deoxy-2'-C-methyluridine by highly diastereoselective homogeneous hydrogenation.

Lemaire S, Houpis I, Wechselberger R, Langens J, Vermeulen WA, Smets N, Nettekoven U, Wang Y, Xiao T, Qu H, Liu R, Jonckers TH, Raboisson P, Vandyck K, Nilsson KM, Farina V. Lemaire S, et al. J Org Chem. 2011 Jan 7;76(1):297-300. doi: 10.1021/jo101822j. Epub 2010 Dec 6. J Org Chem. 2011. PMID: 21133352

5

Carboxylate directed cross-coupling reactions in the synthesis of trisubstituted benzoic acids.

Houpis IN, Huang C, Nettekoven U, Chen JG, Liu R, Canters M. Houpis IN, et al. Org Lett. 2008 Dec 18;10(24):5601-4. doi: 10.1021/ol802349u. Org Lett. 2008. PMID: 19053734

6

Synthesis of (1R,2S)-1-amino-2-vinylcyclopropanecarboxylic acid vinyl-ACCA) derivatives: key intermediates for the preparation of inhibitors of the hepatitis C virus NS3 protease.

Beaulieu PL, Gillard J, Bailey MD, Boucher C, Duceppe JS, Simoneau B, Wang XJ, Zhang L, Grozinger K, Houpis I, Farina V, Heimroth H, Krueger T, Schnaubelt J. Beaulieu PL, et al. J Org Chem. 2005 Jul 22;70(15):5869-79. doi: 10.1021/jo050468q. J Org Chem. 2005. PMID: 16018680

7

Efficient large-scale synthesis of BILN 2061, a potent HCV protease inhibitor, by a convergent approach based on ring-closing metathesis.

Yee NK, Farina V, Houpis IN, Haddad N, Frutos RP, Gallou F, Wang XJ, Wei X, Simpson RD, Feng X, Fuchs V, Xu Y, Tan J, Zhang L, Xu J, Smith-Keenan LL, Vitous J, Ridges MD, Spinelli EM, Johnson M, Donsbach K, Nicola T, Brenner M, Winter E, Kreye P, Samstag W. Yee NK, et al. Among authors: houpis in. J Org Chem. 2006 Sep 15;71(19):7133-45. doi: 10.1021/jo060285j. J Org Chem. 2006. PMID: 16958506

8

Synthesis of PPAR agonist via asymmetric hydrogenation of a cinnamic acid derivative and stereospecific displacement of (S)-2-chloropropionic acid.

Houpis IN, Patterson LE, Alt CA, Rizzo JR, Zhang TY, Haurez M. Houpis IN, et al. Org Lett. 2005 May 12;7(10):1947-50. doi: 10.1021/ol050367e. Org Lett. 2005. PMID: 15876026

9

Discovery of selective 2,4-diaminoquinazoline toll-like receptor 7 (TLR 7) agonists.

Pieters S, McGowan D, Herschke F, Pauwels F, Stoops B, Last S, Embrechts W, Scholliers A, Mostmans W, Van Dijck K, Van Schoubroeck B, Thoné T, De Pooter D, Fanning G, Rosauro ML, Khamlichi MD, Houpis I, Arnoult E, Jonckers THM, Raboisson P. Pieters S, et al. Bioorg Med Chem Lett. 2018 Feb 15;28(4):711-719. doi: 10.1016/j.bmcl.2018.01.014. Epub 2018 Jan 16. Bioorg Med Chem Lett. 2018. PMID: 29366653

10

Synthesis of a peroxime proliferator activated receptor (PPAR) alpha/gamma agonist via stereocontrolled Williamson ether synthesis and stereospecific SN2 reaction of S-2-chloro propionic acid with phenoxides.

Aikins JA, Haurez M, Rizzo JR, Van Hoeck JP, Brione W, Kestemont JP, Stevens C, Lemair X, Stephenson GA, Marlot E, Forst M, Houpis IN. Aikins JA, et al. Among authors: houpis in. J Org Chem. 2005 Jun 10;70(12):4695-705. doi: 10.1021/jo050268e. J Org Chem. 2005. PMID: 15932307

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