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Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice.
Ishimoto T, Lanaspa MA, Le MT, Garcia GE, Diggle CP, Maclean PS, Jackman MR, Asipu A, Roncal-Jimenez CA, Kosugi T, Rivard CJ, Maruyama S, Rodriguez-Iturbe B, Sánchez-Lozada LG, Bonthron DT, Sautin YY, Johnson RJ. Ishimoto T, et al. Among authors: rivard cj. Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4320-5. doi: 10.1073/pnas.1119908109. Epub 2012 Feb 27. Proc Natl Acad Sci U S A. 2012. PMID: 22371574 Free PMC article.
Endogenous fructose production and metabolism in the liver contributes to the development of metabolic syndrome.
Lanaspa MA, Ishimoto T, Li N, Cicerchi C, Orlicky DJ, Ruzycki P, Rivard C, Inaba S, Roncal-Jimenez CA, Bales ES, Diggle CP, Asipu A, Petrash JM, Kosugi T, Maruyama S, Sanchez-Lozada LG, McManaman JL, Bonthron DT, Sautin YY, Johnson RJ. Lanaspa MA, et al. Nat Commun. 2013;4:2434. doi: 10.1038/ncomms3434. Nat Commun. 2013. PMID: 24022321 Free PMC article.
Sucrose induces fatty liver and pancreatic inflammation in male breeder rats independent of excess energy intake.
Roncal-Jimenez CA, Lanaspa MA, Rivard CJ, Nakagawa T, Sanchez-Lozada LG, Jalal D, Andres-Hernando A, Tanabe K, Madero M, Li N, Cicerchi C, Mc Fann K, Sautin YY, Johnson RJ. Roncal-Jimenez CA, et al. Among authors: rivard cj. Metabolism. 2011 Sep;60(9):1259-70. doi: 10.1016/j.metabol.2011.01.008. Epub 2011 Apr 12. Metabolism. 2011. PMID: 21489572 Free PMC article.
Uric acid stimulates fructokinase and accelerates fructose metabolism in the development of fatty liver.
Lanaspa MA, Sanchez-Lozada LG, Cicerchi C, Li N, Roncal-Jimenez CA, Ishimoto T, Le M, Garcia GE, Thomas JB, Rivard CJ, Andres-Hernando A, Hunter B, Schreiner G, Rodriguez-Iturbe B, Sautin YY, Johnson RJ. Lanaspa MA, et al. Among authors: rivard cj. PLoS One. 2012;7(10):e47948. doi: 10.1371/journal.pone.0047948. Epub 2012 Oct 24. PLoS One. 2012. PMID: 23112875 Free PMC article.
High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase.
Ishimoto T, Lanaspa MA, Rivard CJ, Roncal-Jimenez CA, Orlicky DJ, Cicerchi C, McMahan RH, Abdelmalek MF, Rosen HR, Jackman MR, MacLean PS, Diggle CP, Asipu A, Inaba S, Kosugi T, Sato W, Maruyama S, Sánchez-Lozada LG, Sautin YY, Hill JO, Bonthron DT, Johnson RJ. Ishimoto T, et al. Among authors: rivard cj. Hepatology. 2013 Nov;58(5):1632-43. doi: 10.1002/hep.26594. Epub 2013 Oct 8. Hepatology. 2013. PMID: 23813872 Free PMC article.
Fructokinase activity mediates dehydration-induced renal injury.
Roncal Jimenez CA, Ishimoto T, Lanaspa MA, Rivard CJ, Nakagawa T, Ejaz AA, Cicerchi C, Inaba S, Le M, Miyazaki M, Glaser J, Correa-Rotter R, González MA, Aragón A, Wesseling C, Sánchez-Lozada LG, Johnson RJ. Roncal Jimenez CA, et al. Among authors: rivard cj. Kidney Int. 2014 Aug;86(2):294-302. doi: 10.1038/ki.2013.492. Epub 2013 Dec 11. Kidney Int. 2014. PMID: 24336030 Free PMC article.
Endogenous fructose production and fructokinase activation mediate renal injury in diabetic nephropathy.
Lanaspa MA, Ishimoto T, Cicerchi C, Tamura Y, Roncal-Jimenez CA, Chen W, Tanabe K, Andres-Hernando A, Orlicky DJ, Finol E, Inaba S, Li N, Rivard CJ, Kosugi T, Sanchez-Lozada LG, Petrash JM, Sautin YY, Ejaz AA, Kitagawa W, Garcia GE, Bonthron DT, Asipu A, Diggle CP, Rodriguez-Iturbe B, Nakagawa T, Johnson RJ. Lanaspa MA, et al. Among authors: rivard cj. J Am Soc Nephrol. 2014 Nov;25(11):2526-38. doi: 10.1681/ASN.2013080901. Epub 2014 May 29. J Am Soc Nephrol. 2014. PMID: 24876114 Free PMC article.
120 results