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Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice.
Ishimoto T, Lanaspa MA, Le MT, Garcia GE, Diggle CP, Maclean PS, Jackman MR, Asipu A, Roncal-Jimenez CA, Kosugi T, Rivard CJ, Maruyama S, Rodriguez-Iturbe B, Sánchez-Lozada LG, Bonthron DT, Sautin YY, Johnson RJ. Ishimoto T, et al. Among authors: kosugi t. Proc Natl Acad Sci U S A. 2012 Mar 13;109(11):4320-5. doi: 10.1073/pnas.1119908109. Epub 2012 Feb 27. Proc Natl Acad Sci U S A. 2012. PMID: 22371574 Free PMC article.
Fructose induces the inflammatory molecule ICAM-1 in endothelial cells.
Glushakova O, Kosugi T, Roncal C, Mu W, Heinig M, Cirillo P, Sánchez-Lozada LG, Johnson RJ, Nakagawa T. Glushakova O, et al. Among authors: kosugi t. J Am Soc Nephrol. 2008 Sep;19(9):1712-20. doi: 10.1681/ASN.2007121304. Epub 2008 May 28. J Am Soc Nephrol. 2008. PMID: 18508964 Free PMC article.
Uric acid and hypertension: an age-related relationship?
Kosugi T, Nakagawa T, Kamath D, Johnson RJ. Kosugi T, et al. J Hum Hypertens. 2009 Feb;23(2):75-6. doi: 10.1038/jhh.2008.110. Epub 2008 Aug 28. J Hum Hypertens. 2009. PMID: 18754017 No abstract available.
Effect of lowering uric acid on renal disease in the type 2 diabetic db/db mice.
Kosugi T, Nakayama T, Heinig M, Zhang L, Yuzawa Y, Sanchez-Lozada LG, Roncal C, Johnson RJ, Nakagawa T. Kosugi T, et al. Am J Physiol Renal Physiol. 2009 Aug;297(2):F481-8. doi: 10.1152/ajprenal.00092.2009. Epub 2009 May 20. Am J Physiol Renal Physiol. 2009. PMID: 19458127 Free PMC article.
Abnormal angiogenesis in diabetic nephropathy.
Nakagawa T, Kosugi T, Haneda M, Rivard CJ, Long DA. Nakagawa T, et al. Among authors: kosugi t. Diabetes. 2009 Jul;58(7):1471-8. doi: 10.2337/db09-0119. Diabetes. 2009. PMID: 19564458 Free PMC article. No abstract available.
Dietary fructose causes tubulointerstitial injury in the normal rat kidney.
Nakayama T, Kosugi T, Gersch M, Connor T, Sanchez-Lozada LG, Lanaspa MA, Roncal C, Perez-Pozo SE, Johnson RJ, Nakagawa T. Nakayama T, et al. Among authors: kosugi t. Am J Physiol Renal Physiol. 2010 Mar;298(3):F712-20. doi: 10.1152/ajprenal.00433.2009. Epub 2010 Jan 13. Am J Physiol Renal Physiol. 2010. PMID: 20071464 Free PMC article.
High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase.
Ishimoto T, Lanaspa MA, Rivard CJ, Roncal-Jimenez CA, Orlicky DJ, Cicerchi C, McMahan RH, Abdelmalek MF, Rosen HR, Jackman MR, MacLean PS, Diggle CP, Asipu A, Inaba S, Kosugi T, Sato W, Maruyama S, Sánchez-Lozada LG, Sautin YY, Hill JO, Bonthron DT, Johnson RJ. Ishimoto T, et al. Among authors: kosugi t. Hepatology. 2013 Nov;58(5):1632-43. doi: 10.1002/hep.26594. Epub 2013 Oct 8. Hepatology. 2013. PMID: 23813872 Free PMC article.
378 results