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Deconstruction of activity-dependent covalent modification of heme in human neutrophil myeloperoxidase by multistage mass spectrometry (MS(4)).
Biochemistry. 2012 Mar 13;51(10):2065-77. doi: 10.1021/bi201872j. Epub 2012 Mar 1.
Biochemistry. 2012.
PMID: 22352991
Mechanistic characterization of a 2-thioxanthine myeloperoxidase inhibitor and selectivity assessment utilizing click chemistry--activity-based protein profiling.
Ward J, Spath SN, Pabst B, Carpino PA, Ruggeri RB, Xing G, Speers AE, Cravatt BF, Ahn K.
Ward J, et al. Among authors: spath sn.
Biochemistry. 2013 Dec 23;52(51):9187-201. doi: 10.1021/bi401354d. Epub 2013 Dec 9.
Biochemistry. 2013.
PMID: 24320749
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Discovery of 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide (PF-06282999): A Highly Selective Mechanism-Based Myeloperoxidase Inhibitor for the Treatment of Cardiovascular Diseases.
Ruggeri RB, Buckbinder L, Bagley SW, Carpino PA, Conn EL, Dowling MS, Fernando DP, Jiao W, Kung DW, Orr ST, Qi Y, Rocke BN, Smith A, Warmus JS, Zhang Y, Bowles D, Widlicka DW, Eng H, Ryder T, Sharma R, Wolford A, Okerberg C, Walters K, Maurer TS, Zhang Y, Bonin PD, Spath SN, Xing G, Hepworth D, Ahn K, Kalgutkar AS.
Ruggeri RB, et al. Among authors: spath sn.
J Med Chem. 2015 Nov 12;58(21):8513-28. doi: 10.1021/acs.jmedchem.5b00963. Epub 2015 Oct 28.
J Med Chem. 2015.
PMID: 26509551
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Prevalence and diagnosis of hemotrophic mycoplasma infection in research sheep and its effects on hematology variables and erythrocyte membrane fragility.
Hampel JA, Spath SN, Bergin IL, Lim A, Bolin SR, Dyson MC.
Hampel JA, et al. Among authors: spath sn.
Comp Med. 2014 Dec;64(6):478-85.
Comp Med. 2014.
PMID: 25527029
Free PMC article.
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