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Discovery of a series of imidazopyrazine small molecule inhibitors of the kinase MAPKAPK5, that show activity using in vitro and in vivo models of rheumatoid arthritis.
Andrews MJ, Clase JA, Bar G, Tricarico G, Edwards PJ, Brys R, Chambers M, Schmidt W, MacLeod A, Hirst K, Allen V, Birault V, Le J, Harris J, Self A, Nash K, Dixon G. Andrews MJ, et al. Among authors: tricarico g. Bioorg Med Chem Lett. 2012 Mar 15;22(6):2266-70. doi: 10.1016/j.bmcl.2012.01.077. Epub 2012 Jan 31. Bioorg Med Chem Lett. 2012. PMID: 22342143
Discovery of GLPG2451, a Novel Once Daily Potentiator for the Treatment of Cystic Fibrosis.
Van der Plas SE, Kelgtermans H, Mammoliti O, Menet C, Tricarico G, De Blieck A, Joannesse C, De Munck T, Lambin D, Cowart M, Dropsit S, Martina SLX, Gees M, Wesse AS, Conrath K, Andrews M. Van der Plas SE, et al. Among authors: tricarico g. J Med Chem. 2021 Jan 14;64(1):343-353. doi: 10.1021/acs.jmedchem.0c01796. Epub 2021 Jan 5. J Med Chem. 2021. PMID: 33399458
Discovery and Optimization of Orally Bioavailable Phthalazone and Cinnolone Carboxylic Acid Derivatives as S1P2 Antagonists against Fibrotic Diseases.
Mammoliti O, Jansen K, El Bkassiny S, Palisse A, Triballeau N, Bucher D, Allart B, Jaunet A, Tricarico G, De Wachter M, Menet C, Blanc J, Letfus V, Rupčić R, Šmehil M, Poljak T, Coornaert B, Sonck K, Duys I, Waeckel L, Lecru L, Marsais F, Jagerschmidt C, Auberval M, Pujuguet P, Oste L, Borgonovi M, Wakselman E, Christophe T, Houvenaghel N, Jans M, Heckmann B, Sanière L, Brys R. Mammoliti O, et al. Among authors: tricarico g. J Med Chem. 2021 Oct 14;64(19):14557-14586. doi: 10.1021/acs.jmedchem.1c01066. Epub 2021 Sep 28. J Med Chem. 2021. PMID: 34581584
Correction to "Discovery of GLPG2451, a Novel Once Daily Potentiator for the Treatment of Cystic Fibrosis".
Van der Plas SE, Kelgtermans H, Mammoliti O, Menet C, Tricarico G, De Blieck A, Joannesse C, De Munck T, Lambin D, Cowart M, Dropsit S, Martina SLX, Gees M, Wesse AS, Conrath K, Andrews M. Van der Plas SE, et al. Among authors: tricarico g. J Med Chem. 2021 Sep 23;64(18):13933. doi: 10.1021/acs.jmedchem.1c01537. Epub 2021 Sep 14. J Med Chem. 2021. PMID: 34520202 No abstract available.
Large-Scale Modeling of Sparse Protein Kinase Activity Data.
Luukkonen S, Meijer E, Tricarico GA, Hofmans J, Stouten PFW, van Westen GJP, Lenselink EB. Luukkonen S, et al. Among authors: tricarico ga. J Chem Inf Model. 2023 Jun 26;63(12):3688-3696. doi: 10.1021/acs.jcim.3c00132. Epub 2023 Jun 9. J Chem Inf Model. 2023. PMID: 37294674 Free PMC article.
"Good Wine Makes Good Blood": An Integrated Approach to Characterize Autochthonous Apulian Grapevines as Promising Candidates for Healthy Wines.
Sabetta W, Centrone M, D'Agostino M, Difonzo G, Mansi L, Tricarico G, Venerito P, Picardi E, Ceci LR, Tamma G, Caponio F, Montemurro C, Volpicella M. Sabetta W, et al. Among authors: tricarico g. Int J Biol Sci. 2022 Apr 11;18(7):2851-2866. doi: 10.7150/ijbs.70287. eCollection 2022. Int J Biol Sci. 2022. PMID: 35541898 Free PMC article.
34 results