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The alarmin interleukin-33 drives protective antiviral CD8⁺ T cell responses.
Bonilla WV, Fröhlich A, Senn K, Kallert S, Fernandez M, Johnson S, Kreutzfeldt M, Hegazy AN, Schrick C, Fallon PG, Klemenz R, Nakae S, Adler H, Merkler D, Löhning M, Pinschewer DD. Bonilla WV, et al. Among authors: hegazy an. Science. 2012 Feb 24;335(6071):984-9. doi: 10.1126/science.1215418. Epub 2012 Feb 9. Science. 2012. PMID: 22323740
Impaired antibody response causes persistence of prototypic T cell-contained virus.
Bergthaler A, Flatz L, Verschoor A, Hegazy AN, Holdener M, Fink K, Eschli B, Merkler D, Sommerstein R, Horvath E, Fernandez M, Fitsche A, Senn BM, Verbeek JS, Odermatt B, Siegrist CA, Pinschewer DD. Bergthaler A, et al. Among authors: hegazy an. PLoS Biol. 2009 Apr 7;7(4):e1000080. doi: 10.1371/journal.pbio.1000080. PLoS Biol. 2009. PMID: 19355789 Free PMC article.
Development of replication-defective lymphocytic choriomeningitis virus vectors for the induction of potent CD8+ T cell immunity.
Flatz L, Hegazy AN, Bergthaler A, Verschoor A, Claus C, Fernandez M, Gattinoni L, Johnson S, Kreppel F, Kochanek S, Broek Mv, Radbruch A, Lévy F, Lambert PH, Siegrist CA, Restifo NP, Löhning M, Ochsenbein AF, Nabel GJ, Pinschewer DD. Flatz L, et al. Among authors: hegazy an. Nat Med. 2010 Mar;16(3):339-45. doi: 10.1038/nm.2104. Epub 2010 Feb 7. Nat Med. 2010. PMID: 20139992 Free PMC article.
The alarmin IL-33 promotes regulatory T-cell function in the intestine.
Schiering C, Krausgruber T, Chomka A, Fröhlich A, Adelmann K, Wohlfert EA, Pott J, Griseri T, Bollrath J, Hegazy AN, Harrison OJ, Owens BMJ, Löhning M, Belkaid Y, Fallon PG, Powrie F. Schiering C, et al. Among authors: hegazy an. Nature. 2014 Sep 25;513(7519):564-568. doi: 10.1038/nature13577. Epub 2014 Jul 16. Nature. 2014. PMID: 25043027 Free PMC article.
Th2 cells lacking T-bet suppress naive and memory T cell responses via IL-10.
Muñoz M, Hegazy AN, Brunner TM, Holecska V, Marek RM, Fröhlich A, Löhning M. Muñoz M, et al. Among authors: hegazy an. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2002787118. doi: 10.1073/pnas.2002787118. Proc Natl Acad Sci U S A. 2021. PMID: 33526653 Free PMC article.
52 results