Ernst JA - Search Results

1

Mammary tumor regression elicited by Wnt signaling inhibitor requires IGFBP5.

Liu BY, Soloviev I, Huang X, Chang P, Ernst JA, Polakis P, Sakanaka C. Liu BY, et al. Among authors: ernst ja. Cancer Res. 2012 Mar 15;72(6):1568-78. doi: 10.1158/0008-5472.CAN-11-3668. Epub 2012 Feb 3. Cancer Res. 2012. PMID: 22307840

2

The soluble wnt receptor Frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo.

DeAlmeida VI, Miao L, Ernst JA, Koeppen H, Polakis P, Rubinfeld B. DeAlmeida VI, et al. Among authors: ernst ja. Cancer Res. 2007 Jun 1;67(11):5371-9. doi: 10.1158/0008-5472.CAN-07-0266. Cancer Res. 2007. PMID: 17545618

3

Regulation of epithelial branching morphogenesis and cancer cell growth of the prostate by Wnt signaling.

Wang BE, Wang XD, Ernst JA, Polakis P, Gao WQ. Wang BE, et al. Among authors: ernst ja. PLoS One. 2008 May 14;3(5):e2186. doi: 10.1371/journal.pone.0002186. PLoS One. 2008. PMID: 18478098 Free PMC article.

4

Wnt isoform-specific interactions with coreceptor specify inhibition or potentiation of signaling by LRP6 antibodies.

Gong Y, Bourhis E, Chiu C, Stawicki S, DeAlmeida VI, Liu BY, Phamluong K, Cao TC, Carano RA, Ernst JA, Solloway M, Rubinfeld B, Hannoush RN, Wu Y, Polakis P, Costa M. Gong Y, et al. Among authors: ernst ja. PLoS One. 2010 Sep 13;5(9):e12682. doi: 10.1371/journal.pone.0012682. PLoS One. 2010. PMID: 20856934 Free PMC article.

5

Evolutionary divergence in the catalytic activity of the CAM-1, ROR1 and ROR2 kinase domains.

Bainbridge TW, DeAlmeida VI, Izrael-Tomasevic A, Chalouni C, Pan B, Goldsmith J, Schoen AP, Quiñones GA, Kelly R, Lill JR, Sandoval W, Costa M, Polakis P, Arnott D, Rubinfeld B, Ernst JA. Bainbridge TW, et al. Among authors: ernst ja. PLoS One. 2014 Jul 16;9(7):e102695. doi: 10.1371/journal.pone.0102695. eCollection 2014. PLoS One. 2014. PMID: 25029443 Free PMC article.

6

Reconstitution of a frizzled8.Wnt3a.LRP6 signaling complex reveals multiple Wnt and Dkk1 binding sites on LRP6.

Bourhis E, Tam C, Franke Y, Bazan JF, Ernst J, Hwang J, Costa M, Cochran AG, Hannoush RN. Bourhis E, et al. J Biol Chem. 2010 Mar 19;285(12):9172-9. doi: 10.1074/jbc.M109.092130. Epub 2010 Jan 21. J Biol Chem. 2010. PMID: 20093360 Free PMC article.

7

Polyubiquitination of insulin-like growth factor I receptor (IGF-IR) activation loop promotes antibody-induced receptor internalization and down-regulation.

Mao Y, Shang Y, Pham VC, Ernst JA, Lill JR, Scales SJ, Zha J. Mao Y, et al. Among authors: ernst ja. J Biol Chem. 2011 Dec 2;286(48):41852-41861. doi: 10.1074/jbc.M111.288514. Epub 2011 Oct 12. J Biol Chem. 2011. PMID: 21994939 Free PMC article.

8

Effect of Modulating FcRn Binding on Direct and Pretargeted Tumor Uptake of Full-length Antibodies.

Nazarova L, Rafidi H, Mandikian D, Ferl GZ, Koerber JT, Davies CW, Ulufatu S, Ho J, Lau J, Yu SF, Ernst J, Sadowsky JD, Boswell CA. Nazarova L, et al. Mol Cancer Ther. 2020 Apr;19(4):1052-1058. doi: 10.1158/1535-7163.MCT-19-1015. Epub 2020 Feb 5. Mol Cancer Ther. 2020. PMID: 32024685

9

Sustained Brown Fat Stimulation and Insulin Sensitization by a Humanized Bispecific Antibody Agonist for Fibroblast Growth Factor Receptor 1/βKlotho Complex.

Kolumam G, Chen MZ, Tong R, Zavala-Solorio J, Kates L, van Bruggen N, Ross J, Wyatt SK, Gandham VD, Carano RA, Dunshee DR, Wu AL, Haley B, Anderson K, Warming S, Rairdan XY, Lewin-Koh N, Zhang Y, Gutierrez J, Baruch A, Gelzleichter TR, Stevens D, Rajan S, Bainbridge TW, Vernes JM, Meng YG, Ziai J, Soriano RH, Brauer MJ, Chen Y, Stawicki S, Kim HS, Comps-Agrar L, Luis E, Spiess C, Wu Y, Ernst JA, McGuinness OP, Peterson AS, Sonoda J. Kolumam G, et al. Among authors: ernst ja. EBioMedicine. 2015 May 30;2(7):730-43. doi: 10.1016/j.ebiom.2015.05.028. eCollection 2015 Jul. EBioMedicine. 2015. PMID: 26288846 Free PMC article.

10

Characterization of the selective in vitro and in vivo binding properties of crenezumab to oligomeric Aβ.

Meilandt WJ, Maloney JA, Imperio J, Lalehzadeh G, Earr T, Crowell S, Bainbridge TW, Lu Y, Ernst JA, Fuji RN, Atwal JK. Meilandt WJ, et al. Among authors: ernst ja. Alzheimers Res Ther. 2019 Dec 1;11(1):97. doi: 10.1186/s13195-019-0553-5. Alzheimers Res Ther. 2019. PMID: 31787113 Free PMC article.

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