Fabius AW - Search Results

1

Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene.

Meehan M, Parthasarathi L, Moran N, Jefferies CA, Foley N, Lazzari E, Murphy D, Ryan J, Ortiz B, Fabius AW, Chan TA, Stallings RL. Meehan M, et al. Among authors: fabius aw. Mol Cancer. 2012 Feb 5;11:6. doi: 10.1186/1476-4598-11-6. Mol Cancer. 2012. PMID: 22305495 Free PMC article.

2

Loss of the tyrosine phosphatase PTPRD leads to aberrant STAT3 activation and promotes gliomagenesis.

Ortiz B, Fabius AW, Wu WH, Pedraza A, Brennan CW, Schultz N, Pitter KL, Bromberg JF, Huse JT, Holland EC, Chan TA. Ortiz B, et al. Among authors: fabius aw. Proc Natl Acad Sci U S A. 2014 Jun 3;111(22):8149-54. doi: 10.1073/pnas.1401952111. Epub 2014 May 19. Proc Natl Acad Sci U S A. 2014. PMID: 24843164 Free PMC article.

3

Interleukin-1R-associated kinase 2 is a novel modulator of the transforming growth factor beta signaling cascade.

Mullenders J, Fabius AW, van Dongen MM, Kuiken HJ, Beijersbergen RL, Bernards R. Mullenders J, et al. Among authors: fabius aw. Mol Cancer Res. 2010 Apr;8(4):592-603. doi: 10.1158/1541-7786.MCR-09-0386. Epub 2010 Mar 23. Mol Cancer Res. 2010. PMID: 20332216

4

5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft.

Borodovsky A, Salmasi V, Turcan S, Fabius AW, Baia GS, Eberhart CG, Weingart JD, Gallia GL, Baylin SB, Chan TA, Riggins GJ. Borodovsky A, et al. Among authors: fabius aw. Oncotarget. 2013 Oct;4(10):1737-47. doi: 10.18632/oncotarget.1408. Oncotarget. 2013. PMID: 24077805 Free PMC article.

5

Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine.

Turcan S, Fabius AW, Borodovsky A, Pedraza A, Brennan C, Huse J, Viale A, Riggins GJ, Chan TA. Turcan S, et al. Among authors: fabius aw. Oncotarget. 2013 Oct;4(10):1729-36. doi: 10.18632/oncotarget.1412. Oncotarget. 2013. PMID: 24077826 Free PMC article.

6

IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype.

Turcan S, Rohle D, Goenka A, Walsh LA, Fang F, Yilmaz E, Campos C, Fabius AW, Lu C, Ward PS, Thompson CB, Kaufman A, Guryanova O, Levine R, Heguy A, Viale A, Morris LG, Huse JT, Mellinghoff IK, Chan TA. Turcan S, et al. Among authors: fabius aw. Nature. 2012 Feb 15;483(7390):479-83. doi: 10.1038/nature10866. Nature. 2012. PMID: 22343889 Free PMC article.

7

Mutant-IDH1-dependent chromatin state reprogramming, reversibility, and persistence.

Turcan S, Makarov V, Taranda J, Wang Y, Fabius AWM, Wu W, Zheng Y, El-Amine N, Haddock S, Nanjangud G, LeKaye HC, Brennan C, Cross J, Huse JT, Kelleher NL, Osten P, Thompson CB, Chan TA. Turcan S, et al. Among authors: fabius awm. Nat Genet. 2018 Jan;50(1):62-72. doi: 10.1038/s41588-017-0001-z. Epub 2017 Nov 27. Nat Genet. 2018. PMID: 29180699 Free PMC article.

8

An shRNA barcode screen provides insight into cancer cell vulnerability to MDM2 inhibitors.

Brummelkamp TR, Fabius AW, Mullenders J, Madiredjo M, Velds A, Kerkhoven RM, Bernards R, Beijersbergen RL. Brummelkamp TR, et al. Among authors: fabius aw. Nat Chem Biol. 2006 Apr;2(4):202-6. doi: 10.1038/nchembio774. Epub 2006 Feb 13. Nat Chem Biol. 2006. PMID: 16474381

9

Functional identification of cancer-relevant genes through large-scale RNA interference screens in mammalian cells.

Brummelkamp TR, Berns K, Hijmans EM, Mullenders J, Fabius A, Heimerikx M, Velds A, Kerkhoven RM, Madiredjo M, Bernards R, Beijersbergen RL. Brummelkamp TR, et al. Cold Spring Harb Symp Quant Biol. 2004;69:439-45. doi: 10.1101/sqb.2004.69.439. Cold Spring Harb Symp Quant Biol. 2004. PMID: 16117679 No abstract available.

10

A large scale shRNA barcode screen identifies the circadian clock component ARNTL as putative regulator of the p53 tumor suppressor pathway.

Mullenders J, Fabius AW, Madiredjo M, Bernards R, Beijersbergen RL. Mullenders J, et al. Among authors: fabius aw. PLoS One. 2009;4(3):e4798. doi: 10.1371/journal.pone.0004798. Epub 2009 Mar 11. PLoS One. 2009. PMID: 19277210 Free PMC article.

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