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A covalently dimerized recombinant human bone morphogenetic protein-15 variant identifies bone morphogenetic protein receptor type 1B as a key cell surface receptor on ovarian granulosa cells.
Pulkki MM, Mottershead DG, Pasternack AH, Muggalla P, Ludlow H, van Dinther M, Myllymaa S, Koli K, ten Dijke P, Laitinen M, Ritvos O. Pulkki MM, et al. Among authors: van dinther m. Endocrinology. 2012 Mar;153(3):1509-18. doi: 10.1210/en.2010-1390. Epub 2012 Jan 31. Endocrinology. 2012. PMID: 22294741
Identification of a key residue mediating bone morphogenetic protein (BMP)-6 resistance to noggin inhibition allows for engineered BMPs with superior agonist activity.
Song K, Krause C, Shi S, Patterson M, Suto R, Grgurevic L, Vukicevic S, van Dinther M, Falb D, Ten Dijke P, Alaoui-Ismaili MH. Song K, et al. Among authors: van dinther m. J Biol Chem. 2010 Apr 16;285(16):12169-80. doi: 10.1074/jbc.M109.087197. Epub 2010 Jan 4. J Biol Chem. 2010. PMID: 20048150 Free PMC article.
53 results