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PML regulates PER2 nuclear localization and circadian function.
Miki T, Xu Z, Chen-Goodspeed M, Liu M, Van Oort-Jansen A, Rea MA, Zhao Z, Lee CC, Chang KS. Miki T, et al. Among authors: zhao z. EMBO J. 2012 Mar 21;31(6):1427-39. doi: 10.1038/emboj.2012.1. Epub 2012 Jan 24. EMBO J. 2012. PMID: 22274616 Free PMC article.
Circadian behavior of mice deficient in PER1/PML or PER2/PML.
Miki T, Chen-Goodspeed M, Zhao Z, Lee CC. Miki T, et al. Among authors: zhao z. J Circadian Rhythms. 2013 Aug 28;11(1):9. doi: 10.1186/1740-3391-11-9. J Circadian Rhythms. 2013. PMID: 23984853 Free PMC article.
Circadian period 2: a missing beneficial factor in sickle cell disease by lowering pulmonary inflammation, iron overload, and mortality.
Adebiyi MG, Zhao Z, Ye Y, Manalo J, Hong Y, Lee CC, Xian W, McKeon F, Culp-Hill R, D' Alessandro A, Kellems RE, Yoo SH, Han L, Xia Y. Adebiyi MG, et al. Among authors: zhao z. FASEB J. 2019 Sep;33(9):10528-10537. doi: 10.1096/fj.201900246RR. Epub 2019 Jun 29. FASEB J. 2019. PMID: 31260634 Free PMC article.
Overall, we demonstrate that Per1/Per2 is beneficial to counteract elevated systemic inflammation, lung tissue inflammation, and iron overload in SCD.-Adebiyi, M. G., Zhao, Z., Ye, Y., Manalo, J., Hong, Y., Lee, C. C., Xian, W., McKeon, F., Culp-Hill, R., D' Alessan …
Overall, we demonstrate that Per1/Per2 is beneficial to counteract elevated systemic inflammation, lung tissue inflammation, and iron overlo …
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