Paludan SR - Search Results

1

Crystal structure of interleukin-21 receptor (IL-21R) bound to IL-21 reveals that sugar chain interacting with WSXWS motif is integral part of IL-21R.

Hamming OJ, Kang L, Svensson A, Karlsen JL, Rahbek-Nielsen H, Paludan SR, Hjorth SA, Bondensgaard K, Hartmann R. Hamming OJ, et al. Among authors: paludan sr. J Biol Chem. 2012 Mar 16;287(12):9454-60. doi: 10.1074/jbc.M111.311084. Epub 2012 Jan 10. J Biol Chem. 2012. PMID: 22235133 Free PMC article.

2

Type III interferon (IFN) induces a type I IFN-like response in a restricted subset of cells through signaling pathways involving both the Jak-STAT pathway and the mitogen-activated protein kinases.

Zhou Z, Hamming OJ, Ank N, Paludan SR, Nielsen AL, Hartmann R. Zhou Z, et al. Among authors: paludan sr. J Virol. 2007 Jul;81(14):7749-58. doi: 10.1128/JVI.02438-06. Epub 2007 May 16. J Virol. 2007. PMID: 17507495 Free PMC article.

3

An important role for type III interferon (IFN-lambda/IL-28) in TLR-induced antiviral activity.

Ank N, Iversen MB, Bartholdy C, Staeheli P, Hartmann R, Jensen UB, Dagnaes-Hansen F, Thomsen AR, Chen Z, Haugen H, Klucher K, Paludan SR. Ank N, et al. Among authors: paludan sr. J Immunol. 2008 Feb 15;180(4):2474-85. doi: 10.4049/jimmunol.180.4.2474. J Immunol. 2008. PMID: 18250457

4

The p59 oligoadenylate synthetase-like protein possesses antiviral activity that requires the C-terminal ubiquitin-like domain.

Marques J, Anwar J, Eskildsen-Larsen S, Rebouillat D, Paludan SR, Sen G, Williams BRG, Hartmann R. Marques J, et al. Among authors: paludan sr. J Gen Virol. 2008 Nov;89(Pt 11):2767-2772. doi: 10.1099/vir.0.2008/003558-0. J Gen Virol. 2008. PMID: 18931074

5

Differential regulation of the OASL and OAS1 genes in response to viral infections.

Melchjorsen J, Kristiansen H, Christiansen R, Rintahaka J, Matikainen S, Paludan SR, Hartmann R. Melchjorsen J, et al. Among authors: paludan sr. J Interferon Cytokine Res. 2009 Apr;29(4):199-207. doi: 10.1089/jir.2008.0050. J Interferon Cytokine Res. 2009. PMID: 19203244

6

RIG-I-mediated activation of p38 MAPK is essential for viral induction of interferon and activation of dendritic cells: dependence on TRAF2 and TAK1.

Mikkelsen SS, Jensen SB, Chiliveru S, Melchjorsen J, Julkunen I, Gaestel M, Arthur JS, Flavell RA, Ghosh S, Paludan SR. Mikkelsen SS, et al. Among authors: paludan sr. J Biol Chem. 2009 Apr 17;284(16):10774-82. doi: 10.1074/jbc.M807272200. Epub 2009 Feb 18. J Biol Chem. 2009. PMID: 19224920 Free PMC article.

7

Interferon-lambda is functionally an interferon but structurally related to the interleukin-10 family.

Gad HH, Dellgren C, Hamming OJ, Vends S, Paludan SR, Hartmann R. Gad HH, et al. Among authors: paludan sr. J Biol Chem. 2009 Jul 31;284(31):20869-75. doi: 10.1074/jbc.M109.002923. Epub 2009 May 20. J Biol Chem. 2009. PMID: 19457860 Free PMC article.

8

Extracellular 2'-5' oligoadenylate synthetase stimulates RNase L-independent antiviral activity: a novel mechanism of virus-induced innate immunity.

Kristiansen H, Scherer CA, McVean M, Iadonato SP, Vends S, Thavachelvam K, Steffensen TB, Horan KA, Kuri T, Weber F, Paludan SR, Hartmann R. Kristiansen H, et al. Among authors: paludan sr. J Virol. 2010 Nov;84(22):11898-904. doi: 10.1128/JVI.01003-10. Epub 2010 Sep 15. J Virol. 2010. PMID: 20844035 Free PMC article.

9

HSV infection induces production of ROS, which potentiate signaling from pattern recognition receptors: role for S-glutathionylation of TRAF3 and 6.

Gonzalez-Dosal R, Horan KA, Rahbek SH, Ichijo H, Chen ZJ, Mieyal JJ, Hartmann R, Paludan SR. Gonzalez-Dosal R, et al. Among authors: paludan sr. PLoS Pathog. 2011 Sep;7(9):e1002250. doi: 10.1371/journal.ppat.1002250. Epub 2011 Sep 15. PLoS Pathog. 2011. PMID: 21949653 Free PMC article.

10

A coding IRAK2 protein variant compromises Toll-like receptor (TLR) signaling and is associated with colorectal cancer survival.

Wang H, Flannery SM, Dickhöfer S, Huhn S, George J, Kubarenko AV, Lascorz J, Bevier M, Willemsen J, Pichulik T, Schafmayer C, Binder M, Manoury B, Paludan SR, Alarcon-Riquelme M, Bowie AG, Försti A, Weber ANR. Wang H, et al. Among authors: paludan sr. J Biol Chem. 2014 Aug 15;289(33):23123-23131. doi: 10.1074/jbc.M113.492934. Epub 2014 Jun 19. J Biol Chem. 2014. PMID: 24973222 Free PMC article.

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