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Chronic myelogenous leukemia stem and progenitor cells demonstrate chromosomal instability related to repeated breakage-fusion-bridge cycles mediated by increased nonhomologous end joining.
Chakraborty S, Stark JM, Sun CL, Modi H, Chen W, O'Connor TR, Forman SJ, Bhatia S, Bhatia R. Chakraborty S, et al. Among authors: modi h. Blood. 2012 Jun 28;119(26):6187-97. doi: 10.1182/blood-2011-05-352252. Epub 2012 Apr 4. Blood. 2012. PMID: 22493298 Free PMC article.
Genomic instability may originate from imatinib-refractory chronic myeloid leukemia stem cells.
Bolton-Gillespie E, Schemionek M, Klein HU, Flis S, Hoser G, Lange T, Nieborowska-Skorska M, Maier J, Kerstiens L, Koptyra M, Müller MC, Modi H, Stoklosa T, Seferynska I, Bhatia R, Holyoake TL, Koschmieder S, Skorski T. Bolton-Gillespie E, et al. Among authors: modi h. Blood. 2013 May 16;121(20):4175-83. doi: 10.1182/blood-2012-11-466938. Epub 2013 Mar 29. Blood. 2013. PMID: 23543457 Free PMC article.
Janus kinase 2 regulates Bcr-Abl signaling in chronic myeloid leukemia.
Samanta A, Perazzona B, Chakraborty S, Sun X, Modi H, Bhatia R, Priebe W, Arlinghaus R. Samanta A, et al. Among authors: modi h. Leukemia. 2011 Mar;25(3):463-72. doi: 10.1038/leu.2010.287. Epub 2010 Dec 24. Leukemia. 2011. PMID: 21183952 Free PMC article.
Combined BCR-ABL inhibition with lentiviral-delivered shRNA and dasatinib augments induction of apoptosis in Philadelphia-positive cells.
Myssina S, Helgason GV, Serrels A, Jørgensen HG, Bhatia R, Modi H, Baird JW, Mountford JC, Hamilton A, Schemionek M, Koschmieder S, Brunton VG, Holyoake TL. Myssina S, et al. Among authors: modi h. Exp Hematol. 2009 Feb;37(2):206-14. doi: 10.1016/j.exphem.2008.10.013. Epub 2008 Dec 18. Exp Hematol. 2009. PMID: 19100678 Free article.
Modulation of CD47-SIRPα innate immune checkpoint axis with Fc-function detuned anti-CD47 therapeutic antibody.
Narla RK, Modi H, Bauer D, Abbasian M, Leisten J, Piccotti JR, Kopytek S, Eckelman BP, Deveraux Q, Timmer J, Zhu D, Wong L, Escoubet L, Raymon HK, Hariharan K. Narla RK, et al. Among authors: modi h. Cancer Immunol Immunother. 2022 Feb;71(2):473-489. doi: 10.1007/s00262-021-03010-6. Epub 2021 Jul 10. Cancer Immunol Immunother. 2022. PMID: 34247273 Free PMC article.
200 results