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The tumor suppressor gene HIC1 (hypermethylated in cancer 1) is a sequence-specific transcriptional repressor: definition of its consensus binding sequence and analysis of its DNA binding and repressive properties.
Pinte S, Stankovic-Valentin N, Deltour S, Rood BR, Guérardel C, Leprince D. Pinte S, et al. Among authors: rood br. J Biol Chem. 2004 Sep 10;279(37):38313-24. doi: 10.1074/jbc.M401610200. Epub 2004 Jul 1. J Biol Chem. 2004. PMID: 15231840 Free article.
HIC1 (Hypermethylated in Cancer 1) epigenetic silencing in tumors.
Fleuriel C, Touka M, Boulay G, Guérardel C, Rood BR, Leprince D. Fleuriel C, et al. Among authors: rood br. Int J Biochem Cell Biol. 2009 Jan;41(1):26-33. doi: 10.1016/j.biocel.2008.05.028. Epub 2008 Aug 3. Int J Biochem Cell Biol. 2009. PMID: 18723112 Free PMC article. Review.
HIC1 (hypermethylated in cancer 1) SUMOylation is dispensable for DNA repair but is essential for the apoptotic DNA damage response (DDR) to irreparable DNA double-strand breaks (DSBs).
Paget S, Dubuissez M, Dehennaut V, Nassour J, Harmon BT, Spruyt N, Loison I, Abbadie C, Rood BR, Leprince D. Paget S, et al. Among authors: rood br. Oncotarget. 2017 Jan 10;8(2):2916-2935. doi: 10.18632/oncotarget.13807. Oncotarget. 2017. PMID: 27935866 Free PMC article.
HIC1 (Hypermethylated in Cancer 1) modulates the contractile activity of prostate stromal fibroblasts and directly regulates CXCL12 expression.
Dubuissez M, Paget S, Abdelfettah S, Spruyt N, Dehennaut V, Boulay G, Loison I, de Schutter C, Rood BR, Duterque-Coquillaud M, Leroy X, Leprince D. Dubuissez M, et al. Among authors: rood br. Oncotarget. 2020 Nov 10;11(45):4138-4154. doi: 10.18632/oncotarget.27786. eCollection 2020 Nov 10. Oncotarget. 2020. PMID: 33227080 Free PMC article.
Proteomic profiling of high risk medulloblastoma reveals functional biology.
Staal JA, Lau LS, Zhang H, Ingram WJ, Hallahan AR, Northcott PA, Pfister SM, Wechsler-Reya RJ, Rusert JM, Taylor MD, Cho YJ, Packer RJ, Brown KJ, Rood BR. Staal JA, et al. Among authors: rood br. Oncotarget. 2015 Jun 10;6(16):14584-95. doi: 10.18632/oncotarget.3927. Oncotarget. 2015. PMID: 25970789 Free PMC article.
60 results