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Targeting protein lysine methylation and demethylation in cancers.
He Y, Korboukh I, Jin J, Huang J. He Y, et al. Among authors: korboukh i. Acta Biochim Biophys Sin (Shanghai). 2012 Jan;44(1):70-9. doi: 10.1093/abbs/gmr109. Acta Biochim Biophys Sin (Shanghai). 2012. PMID: 22194015 Free PMC article. Review.
Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors.
Liu F, Li F, Ma A, Dobrovetsky E, Dong A, Gao C, Korboukh I, Liu J, Smil D, Brown PJ, Frye SV, Arrowsmith CH, Schapira M, Vedadi M, Jin J. Liu F, et al. Among authors: korboukh i. J Med Chem. 2013 Mar 14;56(5):2110-24. doi: 10.1021/jm3018332. Epub 2013 Feb 27. J Med Chem. 2013. PMID: 23445220 Free PMC article.
An allosteric inhibitor of protein arginine methyltransferase 3.
Siarheyeva A, Senisterra G, Allali-Hassani A, Dong A, Dobrovetsky E, Wasney GA, Chau I, Marcellus R, Hajian T, Liu F, Korboukh I, Smil D, Bolshan Y, Min J, Wu H, Zeng H, Loppnau P, Poda G, Griffin C, Aman A, Brown PJ, Jin J, Al-Awar R, Arrowsmith CH, Schapira M, Vedadi M. Siarheyeva A, et al. Among authors: korboukh i. Structure. 2012 Aug 8;20(8):1425-35. doi: 10.1016/j.str.2012.06.001. Epub 2012 Jul 12. Structure. 2012. PMID: 22795084 Free article.
AMP is an adenosine A1 receptor agonist.
Rittiner JE, Korboukh I, Hull-Ryde EA, Jin J, Janzen WP, Frye SV, Zylka MJ. Rittiner JE, et al. Among authors: korboukh i. J Biol Chem. 2012 Feb 17;287(8):5301-9. doi: 10.1074/jbc.M111.291666. Epub 2012 Jan 3. J Biol Chem. 2012. PMID: 22215671 Free PMC article.
Tri-substituted triazoles as potent non-nucleoside inhibitors of the HIV-1 reverse transcriptase.
De La Rosa M, Kim HW, Gunic E, Jenket C, Boyle U, Koh YH, Korboukh I, Allan M, Zhang W, Chen H, Xu W, Nilar S, Yao N, Hamatake R, Lang SA, Hong Z, Zhang Z, Girardet JL. De La Rosa M, et al. Among authors: korboukh i. Bioorg Med Chem Lett. 2006 Sep 1;16(17):4444-9. doi: 10.1016/j.bmcl.2006.06.048. Epub 2006 Jun 27. Bioorg Med Chem Lett. 2006. PMID: 16806925
12 results