Bräuner-Osborne H - Search Results

1

Biased agonism of the calcium-sensing receptor.

Thomsen AR, Hvidtfeldt M, Bräuner-Osborne H. Thomsen AR, et al. Cell Calcium. 2012 Feb;51(2):107-16. doi: 10.1016/j.ceca.2011.11.009. Epub 2011 Dec 20. Cell Calcium. 2012. PMID: 22192592

2

Functional importance of the Ala(116)-Pro(136) region in the calcium-sensing receptor. Constitutive activity and inverse agonism in a family C G-protein-coupled receptor.

Jensen AA, Spalding TA, Burstein ES, Sheppard PO, O'Hara PJ, Brann MR, Krogsgaard-Larsen P, Bräuner-Osborne H. Jensen AA, et al. J Biol Chem. 2000 Sep 22;275(38):29547-55. doi: 10.1074/jbc.M910023199. J Biol Chem. 2000. PMID: 10835431 Free article.

3

Pharmacological characterization of mouse GPRC6A, an L-alpha-amino-acid receptor modulated by divalent cations.

Christiansen B, Hansen KB, Wellendorph P, Bräuner-Osborne H. Christiansen B, et al. Br J Pharmacol. 2007 Mar;150(6):798-807. doi: 10.1038/sj.bjp.0707121. Epub 2007 Jan 22. Br J Pharmacol. 2007. PMID: 17245368 Free PMC article.

4

Molecular basis for amino acid sensing by family C G-protein-coupled receptors.

Wellendorph P, Bräuner-Osborne H. Wellendorph P, et al. Br J Pharmacol. 2009 Mar;156(6):869-84. doi: 10.1111/j.1476-5381.2008.00078.x. Br J Pharmacol. 2009. PMID: 19298394 Free PMC article. Review.

5

Allosteric modulation of the calcium-sensing receptor.

Jensen AA, Bräuner-Osborne H. Jensen AA, et al. Curr Neuropharmacol. 2007 Sep;5(3):180-6. doi: 10.2174/157015907781695982. Curr Neuropharmacol. 2007. PMID: 19305800 Free PMC article.

6

Chemogenomic discovery of allosteric antagonists at the GPRC6A receptor.

Gloriam DE, Wellendorph P, Johansen LD, Thomsen AR, Phonekeo K, Pedersen DS, Bräuner-Osborne H. Gloriam DE, et al. Chem Biol. 2011 Nov 23;18(11):1489-98. doi: 10.1016/j.chembiol.2011.09.012. Chem Biol. 2011. PMID: 22118683

7

Novel strategies in drug discovery of the calcium-sensing receptor based on biased signaling.

Thomsen AR, Smajilovic S, Bräuner-Osborne H. Thomsen AR, et al. Curr Drug Targets. 2012 Sep 1;13(10):1324-35. doi: 10.2174/138945012802429642. Curr Drug Targets. 2012. PMID: 22702634 Review.

8

Strontium is a biased agonist of the calcium-sensing receptor in rat medullary thyroid carcinoma 6-23 cells.

Thomsen AR, Worm J, Jacobsen SE, Stahlhut M, Latta M, Bräuner-Osborne H. Thomsen AR, et al. J Pharmacol Exp Ther. 2012 Dec;343(3):638-49. doi: 10.1124/jpet.112.197210. Epub 2012 Aug 31. J Pharmacol Exp Ther. 2012. PMID: 22942242 Free PMC article.

9

Delineation of the GPRC6A receptor signaling pathways using a mammalian cell line stably expressing the receptor.

Jacobsen SE, Nørskov-Lauritsen L, Thomsen AR, Smajilovic S, Wellendorph P, Larsson NH, Lehmann A, Bhatia VK, Bräuner-Osborne H. Jacobsen SE, et al. J Pharmacol Exp Ther. 2013 Nov;347(2):298-309. doi: 10.1124/jpet.113.206276. Epub 2013 Sep 5. J Pharmacol Exp Ther. 2013. PMID: 24008333 Free PMC article.

10

G protein-coupled receptor signaling analysis using homogenous time-resolved Förster resonance energy transfer (HTRF®) technology.

Nørskov-Lauritsen L, Thomsen AR, Bräuner-Osborne H. Nørskov-Lauritsen L, et al. Int J Mol Sci. 2014 Feb 13;15(2):2554-72. doi: 10.3390/ijms15022554. Int J Mol Sci. 2014. PMID: 24531140 Free PMC article.

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