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Incidence and nature of testicular toxicity findings in pharmaceutical development.
Sasaki JC, Chapin RE, Hall DG, Breslin W, Moffit J, Saldutti L, Enright B, Seger M, Jarvi K, Hixon M, Mitchard T, Kim JH. Sasaki JC, et al. Among authors: enright b. Birth Defects Res B Dev Reprod Toxicol. 2011 Dec;92(6):511-25. doi: 10.1002/bdrb.20338. Birth Defects Res B Dev Reprod Toxicol. 2011. PMID: 22162370 Review.
Summary of the HESI consortium studies exploring circulating inhibin B as a potential biomarker of testis damage in the rat.
Chapin R, Weinbauer G, Thibodeau MS, Sonee M, Saldutti LP, Reagan WJ, Potter D, Moffit JS, Laffan S, Kim JH, Goldstein RA, Erdos Z, Enright BP, Coulson M, Breslin WJ. Chapin R, et al. Birth Defects Res B Dev Reprod Toxicol. 2013 Feb;98(1):110-8. doi: 10.1002/bdrb.21041. Epub 2013 Jan 30. Birth Defects Res B Dev Reprod Toxicol. 2013. PMID: 23364877
Comparison of rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on the nature and severity of developmental effects.
Theunissen PT, Beken S, Beyer BK, Breslin WJ, Cappon GD, Chen CL, Chmielewski G, De Schaepdrijver L, Enright B, Foreman JE, Harrouk W, Hew KW, Hoberman AM, Hui JY, Knudsen TB, Laffan SB, Makris SL, Martin M, McNerney ME, Siezen CL, Stanislaus DJ, Stewart J, Thompson KE, Tornesi B, Van der Laan JW, Weinbauer GF, Wood S, Piersma AH. Theunissen PT, et al. Among authors: enright b. Crit Rev Toxicol. 2016 Nov;46(10):900-910. doi: 10.1080/10408444.2016.1224807. Epub 2016 Oct 19. Crit Rev Toxicol. 2016. PMID: 27848393 Free PMC article. Review.
Comparing rat and rabbit embryo-fetal developmental toxicity data for 379 pharmaceuticals: on systemic dose and developmental effects.
Theunissen PT, Beken S, Beyer B, Breslin WJ, Cappon GD, Chen CL, Chmielewski G, de Schaepdrijver L, Enright B, Foreman JE, Harrouk W, Hew KW, Hoberman AM, Y Hui J, Knudsen TB, Laffan SB, Makris SL, Martin M, McNerney ME, Siezen CL, Stanislaus DJ, Stewart J, Thompson KE, Tornesi B, Van der Laan JW, Weinbauer GF, Wood S, Piersma AH. Theunissen PT, et al. Among authors: enright b. Crit Rev Toxicol. 2017 May;47(5):402-414. doi: 10.1080/10408444.2016.1224808. Epub 2016 Oct 21. Crit Rev Toxicol. 2017. PMID: 27766926
39 results