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Lysosomal integral membrane protein-2 (LIMP-2/SCARB2) is involved in lysosomal cholesterol export.
Heybrock S, Kanerva K, Meng Y, Ing C, Liang A, Xiong ZJ, Weng X, Ah Kim Y, Collins R, Trimble W, Pomès R, Privé GG, Annaert W, Schwake M, Heeren J, Lüllmann-Rauch R, Grinstein S, Ikonen E, Saftig P, Neculai D. Heybrock S, et al. Among authors: heeren j. Nat Commun. 2019 Aug 6;10(1):3521. doi: 10.1038/s41467-019-11425-0. Nat Commun. 2019. PMID: 31387993 Free PMC article.
Replication of SARS-CoV-2 in adipose tissue determines organ and systemic lipid metabolism in hamsters and humans.
Zickler M, Stanelle-Bertram S, Ehret S, Heinrich F, Lange P, Schaumburg B, Kouassi NM, Beck S, Jaeckstein MY, Mann O, Krasemann S, Schroeder M, Jarczak D, Nierhaus A, Kluge S, Peschka M, Schlüter H, Renné T, Pueschel K, Kloetgen A, Scheja L, Ondruschka B, Heeren J, Gabriel G. Zickler M, et al. Among authors: heeren j. Cell Metab. 2022 Jan 4;34(1):1-2. doi: 10.1016/j.cmet.2021.12.002. Epub 2021 Dec 10. Cell Metab. 2022. PMID: 34895500 Free PMC article.
Fatty acid synthesis suppresses dietary polyunsaturated fatty acid use.
Worthmann A, Ridder J, Piel SYL, Evangelakos I, Musfeldt M, Voß H, O'Farrell M, Fischer AW, Adak S, Sundd M, Siffeti H, Haumann F, Kloth K, Bierhals T, Heine M, Pertzborn P, Pauly M, Scholz JJ, Kundu S, Fuh MM, Neu A, Tödter K, Hempel M, Knippschild U, Semenkovich CF, Schlüter H, Heeren J, Scheja L, Kubisch C, Schlein C. Worthmann A, et al. Among authors: heeren j. Nat Commun. 2024 Jan 2;15(1):45. doi: 10.1038/s41467-023-44364-y. Nat Commun. 2024. PMID: 38167725 Free PMC article.
Annexin A6 modulates TBC1D15/Rab7/StARD3 axis to control endosomal cholesterol export in NPC1 cells.
Meneses-Salas E, García-Melero A, Kanerva K, Blanco-Muñoz P, Morales-Paytuvi F, Bonjoch J, Casas J, Egert A, Beevi SS, Jose J, Llorente-Cortés V, Rye KA, Heeren J, Lu A, Pol A, Tebar F, Ikonen E, Grewal T, Enrich C, Rentero C. Meneses-Salas E, et al. Among authors: heeren j. Cell Mol Life Sci. 2020 Jul;77(14):2839-2857. doi: 10.1007/s00018-019-03330-y. Epub 2019 Oct 29. Cell Mol Life Sci. 2020. PMID: 31664461 Free PMC article.
Aryl Hydrocarbon Receptor Activity in Hepatocytes Sensitizes to Hyperacute Acetaminophen-Induced Hepatotoxicity in Mice.
Schuran FA, Lommetz C, Steudter A, Ghallab A, Wieschendorf B, Schwinge D, Zuehlke S, Reinders J, Heeren J, Lohse AW, Schramm C, Herkel J, Carambia A. Schuran FA, et al. Among authors: heeren j. Cell Mol Gastroenterol Hepatol. 2021;11(2):371-388. doi: 10.1016/j.jcmgh.2020.09.002. Epub 2020 Sep 12. Cell Mol Gastroenterol Hepatol. 2021. PMID: 32932016 Free PMC article.
236 results