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The C terminus of Bax inhibitor-1 forms a Ca2+-permeable channel pore.
Bultynck G, Kiviluoto S, Henke N, Ivanova H, Schneider L, Rybalchenko V, Luyten T, Nuyts K, De Borggraeve W, Bezprozvanny I, Parys JB, De Smedt H, Missiaen L, Methner A. Bultynck G, et al. Among authors: kiviluoto s. J Biol Chem. 2012 Jan 20;287(4):2544-57. doi: 10.1074/jbc.M111.275354. Epub 2011 Nov 28. J Biol Chem. 2012. PMID: 22128171 Free PMC article.
Bax Inhibitor-1-mediated Ca2+ leak is decreased by cytosolic acidosis.
Kiviluoto S, Luyten T, Schneider L, Lisak D, Rojas-Rivera D, Welkenhuyzen K, Missaen L, De Smedt H, Parys JB, Hetz C, Methner A, Bultynck G. Kiviluoto S, et al. Cell Calcium. 2013 Sep;54(3):186-92. doi: 10.1016/j.ceca.2013.06.002. Epub 2013 Jul 16. Cell Calcium. 2013. PMID: 23867001
The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA²⁺-filling state.
Lisak DA, Schacht T, Enders V, Habicht J, Kiviluoto S, Schneider J, Henke N, Bultynck G, Methner A. Lisak DA, et al. Among authors: kiviluoto s. Biochim Biophys Acta. 2015 Sep;1853(9):2104-14. doi: 10.1016/j.bbamcr.2015.03.002. Epub 2015 Mar 9. Biochim Biophys Acta. 2015. PMID: 25764978 Free article.
IP3R2 levels dictate the apoptotic sensitivity of diffuse large B-cell lymphoma cells to an IP3R-derived peptide targeting the BH4 domain of Bcl-2.
Akl H, Monaco G, La Rovere R, Welkenhuyzen K, Kiviluoto S, Vervliet T, Molgó J, Distelhorst CW, Missiaen L, Mikoshiba K, Parys JB, De Smedt H, Bultynck G. Akl H, et al. Among authors: kiviluoto s. Cell Death Dis. 2013 May 16;4(5):e632. doi: 10.1038/cddis.2013.140. Cell Death Dis. 2013. PMID: 23681227 Free PMC article.
19 results