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The C terminus of Bax inhibitor-1 forms a Ca2+-permeable channel pore.
Bultynck G, Kiviluoto S, Henke N, Ivanova H, Schneider L, Rybalchenko V, Luyten T, Nuyts K, De Borggraeve W, Bezprozvanny I, Parys JB, De Smedt H, Missiaen L, Methner A. Bultynck G, et al. Among authors: de smedt h, de borggraeve w. J Biol Chem. 2012 Jan 20;287(4):2544-57. doi: 10.1074/jbc.M111.275354. Epub 2011 Nov 28. J Biol Chem. 2012. PMID: 22128171 Free PMC article.
Polycystin-2 activation by inositol 1,4,5-trisphosphate-induced Ca2+ release requires its direct association with the inositol 1,4,5-trisphosphate receptor in a signaling microdomain.
Sammels E, Devogelaere B, Mekahli D, Bultynck G, Missiaen L, Parys JB, Cai Y, Somlo S, De Smedt H. Sammels E, et al. Among authors: de smedt h. J Biol Chem. 2010 Jun 11;285(24):18794-805. doi: 10.1074/jbc.M109.090662. Epub 2010 Apr 7. J Biol Chem. 2010. PMID: 20375013 Free PMC article.
Endoplasmic-reticulum calcium depletion and disease.
Mekahli D, Bultynck G, Parys JB, De Smedt H, Missiaen L. Mekahli D, et al. Among authors: de smedt h. Cold Spring Harb Perspect Biol. 2011 Jun 1;3(6):a004317. doi: 10.1101/cshperspect.a004317. Cold Spring Harb Perspect Biol. 2011. PMID: 21441595 Free PMC article. Review.
Bax Inhibitor-1-mediated Ca2+ leak is decreased by cytosolic acidosis.
Kiviluoto S, Luyten T, Schneider L, Lisak D, Rojas-Rivera D, Welkenhuyzen K, Missaen L, De Smedt H, Parys JB, Hetz C, Methner A, Bultynck G. Kiviluoto S, et al. Among authors: de smedt h. Cell Calcium. 2013 Sep;54(3):186-92. doi: 10.1016/j.ceca.2013.06.002. Epub 2013 Jul 16. Cell Calcium. 2013. PMID: 23867001
The BH4 domain of anti-apoptotic Bcl-XL, but not that of the related Bcl-2, limits the voltage-dependent anion channel 1 (VDAC1)-mediated transfer of pro-apoptotic Ca2+ signals to mitochondria.
Monaco G, Decrock E, Arbel N, van Vliet AR, La Rovere RM, De Smedt H, Parys JB, Agostinis P, Leybaert L, Shoshan-Barmatz V, Bultynck G. Monaco G, et al. Among authors: de smedt h. J Biol Chem. 2015 Apr 3;290(14):9150-61. doi: 10.1074/jbc.M114.622514. Epub 2015 Feb 13. J Biol Chem. 2015. PMID: 25681439 Free PMC article.
Inhibition of the inositol trisphosphate receptor of mouse eggs and A7r5 cells by KN-93 via a mechanism unrelated to Ca2+/calmodulin-dependent protein kinase II antagonism.
Smyth JT, Abbott AL, Lee B, Sienaert I, Kasri NN, De Smedt H, Ducibella T, Missiaen L, Parys JB, Fissore RA. Smyth JT, et al. Among authors: de smedt h. J Biol Chem. 2002 Sep 20;277(38):35061-70. doi: 10.1074/jbc.M202928200. Epub 2002 Jul 16. J Biol Chem. 2002. PMID: 12121980 Free article.
242 results