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Multitasking in the mitochondrion by the ATP-dependent Lon protease.
Venkatesh S, Lee J, Singh K, Lee I, Suzuki CK. Venkatesh S, et al. Among authors: singh k. Biochim Biophys Acta. 2012 Jan;1823(1):56-66. doi: 10.1016/j.bbamcr.2011.11.003. Epub 2011 Nov 18. Biochim Biophys Acta. 2012. PMID: 22119779 Free PMC article. Review.
CODAS syndrome is associated with mutations of LONP1, encoding mitochondrial AAA+ Lon protease.
Strauss KA, Jinks RN, Puffenberger EG, Venkatesh S, Singh K, Cheng I, Mikita N, Thilagavathi J, Lee J, Sarafianos S, Benkert A, Koehler A, Zhu A, Trovillion V, McGlincy M, Morlet T, Deardorff M, Innes AM, Prasad C, Chudley AE, Lee IN, Suzuki CK. Strauss KA, et al. Among authors: singh k. Am J Hum Genet. 2015 Jan 8;96(1):121-35. doi: 10.1016/j.ajhg.2014.12.003. Am J Hum Genet. 2015. PMID: 25574826 Free PMC article.
Bi-allelic mutations of LONP1 encoding the mitochondrial LonP1 protease cause pyruvate dehydrogenase deficiency and profound neurodegeneration with progressive cerebellar atrophy.
Nimmo GAM, Venkatesh S, Pandey AK, Marshall CR, Hazrati LN, Blaser S, Ahmed S, Cameron J, Singh K, Ray PN, Suzuki CK, Yoon G. Nimmo GAM, et al. Among authors: singh k. Hum Mol Genet. 2019 Jan 15;28(2):290-306. doi: 10.1093/hmg/ddy351. Hum Mol Genet. 2019. PMID: 30304514 Free PMC article.
Identification of a new motif required for the 3'-5' exonuclease activity of Escherichia coli DNA polymerase I (Klenow fragment): the RRRY motif is necessary for the binding of single-stranded DNA substrate and the template strand of the mismatched duplex.
Kukreti P, Singh K, Ketkar A, Modak MJ. Kukreti P, et al. Among authors: singh k. J Biol Chem. 2008 Jun 27;283(26):17979-90. doi: 10.1074/jbc.M801053200. Epub 2008 Apr 29. J Biol Chem. 2008. PMID: 18448432 Free PMC article.
9,446 results